便携式睡眠呼吸暂停低通气监测仪的研制

【作者】 金星亮；

【导师】 陈真诚；

【作者基本信息】 中南大学 ， 生物医学工程， 2010， 硕士

【摘要】 阻塞性睡眠呼吸暂停综合征是一种严重威胁人类健康的常见多发病,只是近30年来才逐渐被人们关注。是一种由于某些原因而导致上呼吸道阻塞,睡眠时有呼吸暂停,伴有缺氧、鼾声、白天嗜睡等症状的一种较复杂的疾病。它不仅影响人们的睡眠质量,还会引起高血压、心脑血管疾病等疾病,对人的健康危害极大。目前,医学上对阻塞性睡眠呼吸暂停综合征的预防、诊断和治疗受到了广泛的重视,因此研制一种便携式睡眠监测仪在临床上具有重要的意义。本文基于光电容积法和朗伯-比尔定律,提出了脉率和血氧饱和度的算法,设计并实现了一种低功耗、体积小、价格便宜、适合家庭使用的睡眠呼吸暂停低通气监测仪。硬件设计上,通过NELLCOR指夹透射式血氧探头和相关驱动电路来采集人体脉搏波信号；通过HONEYWELL呼吸传感器提取鼻呼吸压力信号；设计并实现了人机交互式接口、时钟模块、存储模块、USB数据通信模块等。在软件设计上,在IAR平台上采用C430和汇编的混合编程完成底层驱动程序,实现了数据的采集、预处理、显示、存储和传输,实现了脉率和血氧饱和度的检测算法,同时,采用Visual C++作为开发平台,设计并实现了测试仪配套的PC机端软件系统,实现了生理参数的实时显示与健康评估。通过系统测试表明,该监测仪各功能模块运行良好,整体功能完备,能有效提取脉搏波和呼吸信号,算出脉率和血氧饱和度,并结合呼吸信号,对人体睡眠状况进行评估。更多还原

【Abstract】 Obstructive sleep apnea syndrome(OSAS) is a serious threat to human health,which attracted widespread concern in the past 30 years. OSAS is sleep-breathing disorder characterized by a set of episodes of total and/or partial cessation of respiratory airflow while patient is asleep, also coupled with low oxygen saturation, snore and somnolence during the daytime. OSAS not only affects people’s sleep quality, but also can lead to hypertension, cardiovascular diseases, etc. It becomes more and more important in the prevention, diagnosis and treatment of OSAS presently. Consequently, There is important significance in clinical to develop a portable sleep detecting device.Based on the method of photoelectric plethysmography and the Beer-Lambert Law, the algorithm of pulse frequence and oxygen saturation was present, the portable sleep detecting device characterized by low power dissipation, small size, cheap and suitable for family use was developed. In the part of hardware design,photoplethysmogram was detected with NELLCOR probe and relevant driver circuit; nasal respiratory wave was detected with HONEYWELL respiratory pressure sensor; In the part of software design, the driver is written with the C language on the platform of IAR. The fuction of data gathering, preprocedding, display, save and comminication was realized. The patient monitoring and diagnosis system was designed on the platform of VC++ 6.0, which can display the detected data and generate diagnosis result report.The system testing and clinical experiment was established, the sleep detecting device work well, which can detect photoplethysmogram and respiratory wave effectively, work out the pulse frequency and oxygen saturation, generate diagnosis report of sleep finally.更多还原