【作者】 冯志强；

【导师】 董万利；

【作者基本信息】 苏州大学 ， 神经病学， 2010， 硕士

【摘要】 目的:探讨血管性痴呆患者检测颈动脉粥样硬化的临床意义。方法:经临床确诊的血管性痴呆患者30例,对照组30例。利用高频超声探测颈动脉内-中膜厚度(IMT)及粥样硬化斑块形成情况。结果:血管性痴呆组的IMT增厚、粥样硬化斑块发生率明显高于对照组(P<0.05);血管性痴呆组中软斑检出率高于硬斑及混合斑(P<0.05)。结论:血管性痴呆组患者的IMT及粥样硬化斑块形成率明显高于对照组,血管性痴呆组检出斑块中软斑占优势。高频超声是检测血管性痴呆患者颈动脉粥样硬化的简便而有效的方法,具有重要的临床价值。更多还原

【Abstract】 Objective : To investigate the clinical significance of high-frequency ultrasound evaluation of vascular dementia in elderly patients with carotid atherosclerosis.Methods:30 cases of vascular dementia were assigned to vascular dementia group and 30 healths were chosen as controls which match the vascular dementia group in human basic data. The high-frequency ultrasound was used to detect the intima-media thickness (IMT) and the atherosclerotic plaque formed within the carotid.Results:The incidence of carotid atherosclerosis and its plaque formation in vascular dementia group were significantly higher than those in control group.Compared with the control group, the IMT was thicker, the plaque formation was much more in vascular dementia group (P<0.05) and the character of the plaque was mainly soft in the group of vascular dementia, in other words, less were hard plaques and mixed plaques(P<0.05).Conclusion:The atherosclerotic plaque formation rate in patients with vascular dementia was significantly higher than that in the control group.High-frequency ultrasound is a simple and effective method in detecting carotid atherosclerosis, of which has important clinical value.更多还原