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5%阿维菌素·噻螨酮水乳剂的研制
Research and Preparation of Abamectin-Hexythiazox 5% Emulsion in Water
【作者】 王小天;
【导师】 邓新平;
【作者基本信息】 西南大学 , 农药学, 2010, 硕士
【摘要】 农药水乳剂以水为载体,减少了对环境的污染,并降低了生产成本,在农药新剂型开发中占有重要的地位。本实验以防治成螨效果好的阿维菌素和对幼螨、螨卵防效高的噻螨酮为有效成分,按照5%阿维菌素·噻螨酮乳油登记的比例(阿维菌素:噻螨酮=1:9),在室内生测验证具有明显增效作用的基础上,进行了5%阿维菌素·噻螨酮水乳剂的研制。主要研究结果如下:1.室内生物活性测定结果:阿维菌素和噻螨酮复配,对叶螨雌成虫及螨卵的共毒系数(CTC)分别为215和194,远大于120,有明显增效作用。2.5%阿维菌素·噻螨酮水乳剂优选配方为:阿维菌素0.5%(质量分数,下同)噻螨酮4.5%有机溶剂13%甲苯和N,N-二甲基吡咯烷酮(质量比10:3)乳化剂4%Span-20和Tween-20的混合物(质量比为1:3)丙二醇5%水补足至100%3.5%阿维菌素·噻螨酮水乳剂的质量指标外观乳白色均相液体阿维菌素,质量分数%≥0.5噻螨酮,质量分数%≥4.5pH值7.12乳液稳定性(稀释200倍)合格低温稳定性合格热贮稳定性合格4.田间药效实验表明:5%阿维菌素·噻螨酮水乳剂对豇豆叶螨有很好的防治效果,18g/hm2处理药后7、14 d的防效达93.96%和96.18%,明显优于对照药剂5%阿维菌素乳油、5%噻螨酮乳油的防效。该药剂不但防效理想、持效期较长,且安全性良好。推荐防治豇豆叶螨的有效成分使用量为9-18g/hm2。
【Abstract】 Emulsion in water (EW) is with water as the carrier, and plays an important role in development of new formulations owing to its reducing environmental pollution and production costs. Avermectin exhibits excellent control effect on adult mites while hexythiazox expresses good effect on larval and eggs mites. In the current study, according to the registration rate of 5% avermectin·hexythiazox EC formulation (avermectin:hexythiazox=1:9),5% abamectin-hexythiazox EW is developed based on the indoor bioassay with obvious synergism effects on Tetranychus cinnabarinus.The main results are as follows:1. The effects of indoor bioassayThe co-toxicity coefficient (CTC) of the combination of abamectin with hexythiazox to female adult mites and mite eggs are 215 and 194, respectively, far larger than 120, indicating there is obvious synergism effect of the combination.2.5% avermectin·hexythiazox EW formuLation Abamectin 0.5%(percentage composition) Hexythiazox 4.5% (percentage composition) Organic solvent 13% toluene and N, N-2-methyl-pyrrolidone (10:3) Emulsifier 4% Span-20 and Tween-20 (1:3) Propylene glycol 5% Water Complement to 100%3. Quality indicators of 5% avermectin·hexythiazox EW Appearance Uniform milky white Abamectin (%)≥0.5 Hexythiazox (%)≥4.5 pH 7.12 Emulsion stability Qualified Low temperature stability Qualified Hot storage stability Qualified4. Field trials results show that there was an excellent effect of 5% avermectin·hexythiazox EW on cowpea spider mites. After 7 d and 14 d treatments at the dosage of 18 g/hm~2, the correction control efficacy reached 93.96% and 96.18%, respectively, much better than the control efficacy. The formulation has an ideal control effect, long effective duration and high security. The effective ingredients of 5% avermectin· hexythiazox EW at a dosage of 9 to 18 g/hm2 was recommended to control cowpeaspider mites.
【Key words】 avermectin; hexythiazox; EW; formula selection; control efficacy;