【作者】 邵淑慧；

【导师】 谢晶日；

【作者基本信息】 黑龙江中医药大学 ， 中医学， 2009， 硕士

【摘要】 慢性萎缩性胃炎(Chronic Atrophic Gastritis,CAG)是以胃粘膜上皮遭到反复损害后导致的粘膜固有腺体的萎缩甚至消失为病理特点的消化系统的常见病,是慢性胃炎(Chronic Gastritis)的一种类型。临床表现多见上腹部隐痛、胀闷、食欲不振、嗳气等症状,其病理表现以胃粘膜固有腺体萎缩、粘膜变薄、粘膜肌层变厚、胃酸分泌减少为主,常伴有肠上皮化生(intestinal metapIasia,IM)、异型增生(dysplasia,Dys)。本文根据大量文献资料阐述了慢性萎缩性胃炎的中西医研究进展,从其病因病机、诊断、治疗等方面进行论述,并且从病因病机、辨证、治疗用药等方面总结导师谢晶日教授治疗慢性萎缩性胃炎的思路,并结合导师经治的3例典型慢性萎缩性胃炎患者探讨CAG的诊治。在病因病机上导师认为(1)脾胃气阴两虚是本病的基本发病原因;(2)血瘀热毒是本病的常见致病因素。在治疗上导师认为(1)益气养阴是治疗本病的有效策略;(2)活血解毒是逆转本病的治疗关键。更多还原

【Abstract】 Chronic Atrophic Gastritis(CAG) is a kind of digestive diseases with the principal pathological characteristics of the inherent glandular atrophy or even disappear caused by repeated damage to gastric mucosal.Upper abdominal pain,bulging nausea,loss of appetite and other symptoms are the clinical manifestations of CAG.And the mainly pathological manifestations are gastric mucosal inner inherent glandular atrophy,thinner gastric mucosa, thicker mucosal musculature,less secretion of gastric acid,and often accompanied by intestinal metaplasia or dysplasia.According to mass literature data,the development of CAG in integrated medicine is expatiated,and the etiology,pathogenesis,diagnosis and treatment of CAG are discussed.Through research on three CAG patients of professor XIE Jing-ri,thoughts of therapy of CAG is summarized from etiology,pathogenesis,dialectics and therapeutic medication.From etiology and pathogenesis,professor XIE holds that asthenia of the spleen and stomach and insufficiency of Qi and Yin are the immanent cause of CAG,and blood stasis and retention of damp-heat are the fundamental cause of CAG.And from therapy,professor XIE holds that the method of benefiting Qi, nourishing Yin,promoting brood flew and detoxicating is a fundamental method of treating CAG.更多还原