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子宫腺肌病发病相关因素及中医证候分布特点临床调查研究
Research on the Illness Related Factors and the Type Characteristics of TCM Syndromes of the Adenomyosis
【作者】 侯晓;
【导师】 叶青;
【作者基本信息】 山东中医药大学 , 中医妇科学, 2009, 硕士
【摘要】 目的:本研究旨在了解子宫腺肌病发病相关因素,并对其中医证候分布特点进行探讨。方法:采用病例——对照的研究方法,对子宫腺肌病患者及健康女性的临床资料进行统计分析,找出本病发病的相关因素,同时对子宫腺肌病患者症状进行统计分析,探讨本病中医证候分布情况及辨证特点。结果:1.通过x~2检验和t检验,找出病例组与对照组中差异性比较有统计学意义的因素,再将上述因素进行Logistic回归分析,得出子宫腺肌病发病的危险因素为:年龄处于育龄期、长期从事脑力劳动、月经过多、经期延长或崩漏、原发性痛经史、妊娠次数多、采取宫内节育器避孕、多次宫腔操作史、子宫肌瘤病史及情志异常等,保护因素为月经后期或闭经。2.根据聚类分析结果,可将子宫腺肌病分为气滞血瘀、热蕴血瘀、痰瘀互结、肾虚血瘀、气虚血瘀、寒凝血瘀六大证型。结论:1.总结了子宫腺肌病的10种发病危险因素和1种保护性因素。2.运用聚类分析等统计方法对中医基本证型进行分类是有帮助的。3.当前开展子宫腺肌病发病相关因素及中医证候分布特点的流调工作对指导临床有一定实际意义。
【Abstract】 Objective:To explorer the relevant factors of Adenomyosis patients and to summarize the syndromes distribution regularity and the characteristics of syndrome diferentiation. Method:Used case-control study methods,the patients and the healthy women were statistical analysis by clinical data in order to observe the relevant factors and the syndromes distribution regularity and the characteristics of syndrome diferentiation. Results: 1. The chi-square test suggests:the differences of some factorsh-ave statistically significant between the case group and the control group. Risk factors of Adenomyosis: logistic regression suggests: age,brainworker,the times of the operation in uterus, intrauterine device (IUD) contraception manner,pregnancy and delivery, menostaxis, menorrhagia,primary dysmenorrhea,emotional upsets,the medical history of hysteromyoma are the risk factors. Delayed menstrual cycle is the protectirefactors of Adenomyosis. 2. According to clustera nalysis, the symptoms of Adenomyosis patients could be divided into six nests, including qi stagnation and blood stasis type, blood stasis and heat accumulation type, kidney deficiency and blood stasis type, intermingled phlegm and blood stasis type, qi deficiency and blood stasis type and cold coagulation and blood stasis type.Conclusion:1.Nine risk factors and a protectirefactors of Adenomyosis are generalized. 2.Cluster analysis is helpful to classification of elementary syndromes of TCM. 3.It is significant practically to carry out epidemiological study of syndromes of TCM of Adenomyosis.
【Key words】 Adenomyosis; the illness related factors; the syndrome distribution regularity; logistic regerssion; cluster analysis;
- 【网络出版投稿人】 山东中医药大学 【网络出版年期】2010年 07期
- 【分类号】R271.9
- 【被引频次】3
- 【下载频次】225