【作者】 温小琴；

【导师】 费俊杰；

【作者基本信息】 湘潭大学 ， 分析化学， 2008， 硕士

【摘要】 纳米材料(0.1~100 nm)因其独特的拓扑结构和优异的电学性能在电化学以及电分析化学领域中得到越来越广泛的应用,尤其是在新型化学修饰电极的制备与应用方面。基于纳米材料的优异特性,本论文制备了几种纳米结构电极并用来研究环境内分泌干扰物(己烯雌酚和氟乐灵)以及药物橙皮甙的电化学行为,并在此基础上建立了他们的分析检测方法。这些研究结果拓展了纳米结构电极在电分析化学中的重要意义。研究的主要内容有:1.在纳米结构电极上研究了环境内分泌干扰物氟乐灵的电化学响应。通过将多壁碳纳米管(MWNTs)分散在表面活性剂双十六烷基磷酸(DHP)中,然后通过滴涂的方法即可在电极表面构建了纳米结构电极。实验表明制备的纳米结构电极能够减少氟乐灵的电化学还原过电位,并显著增加峰电流,在此基础上提出了一种高灵敏检测氟乐灵的电化学分析方法。2.在单壁碳纳米管膜修饰电极研究了橙皮甙的电化学行为。橙皮甙在单壁碳纳米管膜修饰电极上表现出灵敏的电化学响应。基于橙皮甙在修饰电极上的优良电化学特性,建立了一种测定橙皮甙的伏安检测方法并优化了各测定参数。方法用于陈皮中橙皮甙的测定,得到满意的结果。3.制备了多壁碳纳米管/纳米铂复合膜修饰电极,对电极的表征和性能进行了研究,并在该电极上用多种电化学方法对橙皮甙在的电化学行为进行了研究,实验表明橙皮甙在复合膜修饰电极上的电化学响应明显比在裸玻电极以及MWNTs-DHP复合膜修饰电极上的要大。据此对实验参数进行了优化,建立了一种检测橙皮甙的新方法。4.制备了纳米铂溶胶,并将单壁碳纳米管(SWNTs)与纳米铂结合,构建了均一、稳定的纳米复合膜修饰电极,并详细考察了环境内分泌干扰物己烯雌酚在纳米复合膜修饰电极上的电化学行为。单壁碳纳米管/纳米铂复合膜能显著提高己烯雌酚的电化学响应及其测定的灵敏度。据此建立了一种新的检测己烯雌酚的高灵敏度方法。更多还原

【Abstract】 Nano-materials, with sizes in the range of 0.1-100 nm, because of their unique architecture and remarkable electrical properties, are widely used in electrochemistry and electroanlytical chemistry, especially in the preparation and application of chemically modified electrode (CME). In this paper, several nano-structred electrodes were fabricated based on the especial properties of nano-materials, and successfully applied to environmental endocrine disrupting chemicals and pharmaic analysis analysis and studies on kinetics of electrochemical process. The results confirm that nano-interfaces play important roles in electroanalyticl chemistry. The focus of this paper has been listed as follows:1. The electroanalytical behaviors of the endocrine-disrupting chemical trifluralin have been studied at a nanostructuring electrode firstly. The nanostructuring electrode was fabricated by coating a uniform multi-wall carbon nanotubes (MWNTs) film on glassy carbon electrode (GCE). The reduction peak currents of trifluralin increased remarkably and the reduction peak potential shifted positively at the MWNTs film modified GCE, compared with that at a bare GCE. The results showed that this nanostructuring electrode exhibited excellent enhancement effects on the electrochemical reduction of trifluralin. Consequently, a simple and sensitive electroanalytical method was developed for the determination of trifluralin.2. A convenient and sensitive electrochemical method is described for the determination of hesperidin based on the unique properties of a single-wall carbon nanotubes (SWNTs) thin film firstly. The electrochemical behavior of hesperidin at the SWNTs film-coated glassy carbon electrode (GCE) was investigated in detail, showing that the SWNTs-coated GCE exhibits electrocatalytic activity to the electrochemical behavior of hesperidin. The experimental parameters, which influence the current of hesperidin, were optimized.3. The voltammetric behaviour of hesperidin was investigated by linear sweep voltammetry and cyclic voltammetry at platinum nanoparticle/MWNTs nanocomposites of glassy carbon electrodes. Compared with the bare GC electrode and MWNTs film modified GC electrode, the peak currents at the MWNTs/Ptnano composite film modified GC electrode was enhanced greatly. The experimental parameters were optimized. The method has been applied successfully to the determination of hesperidin in Chinese crude drugs.4. Platinum nanoparticles (Ptnano) were prepared and used in combination with single-wall carbon nanotubes (SWNTs) for fabricating electrochemical sensors with remarkably improved sensitivity toward diethylstilbestrol (DES). The glassy carbon (GC) electrode modified with SWNTs/Ptnano composite film exhibited excellent electrochemical behaviors toward the redox of DES. Compared with the bare GC electrode and SWNTs film modified GC electrode, the redox peak currents at the SWNTs/Ptnano composite film modified GC electrode was enhanced greatly. The experimental parameters, which influence the current of DES, were optimized.更多还原