【作者】 岳亚杰；

【导师】 高俊山；

【作者基本信息】 哈尔滨理工大学 ， 控制理论与控制工程， 2007， 硕士

【摘要】 青霉素被广泛用于兽药中用来预防及治疗奶牛疾病,如果频繁或超剂量使用,就会使牛奶中残留一定量的青霉素。由于牛奶与人们的日常生活息息相关,人长期饮用或食用有青霉素残留的牛乳或乳制品,就会严重影响食用者的身体健康。传统的青霉素检测方法有很多,但这些方法都具有测试时间长、操作繁琐、测试精度低、费用高等缺点。生物传感器在当前电化学和电分析化学的研究领域十分活跃,目前已经应用到生命科学、环境科学、分析科学、材料科学等许多方面。由于其所特有的检测快速、灵敏度高、专一性强、简单经济等优点,较之青霉素残留的传统检测方法,更易于实现现场检测。因此,本文应用离子敏场效应管作为传感器来测定青霉素的浓度,并以TMS320LF2407A为系统的控制核心,进行了青霉素浓度测试系统的设计。由于MOSFET与ISFET具有相似的结构,因此本文首先从MOSFET器件性能出发,详细分析了ISFET的特性,从而得出青霉素浓度与电信号之间存在一定的函数关系,在此基础上选择电流测量法对传感器的电信号进行读取。然后以TMS320LF2407A为控制核心,对测试系统的外围电路进行设计,包括传感器的放大与滤波电路、A/D转换电路、存储器扩展电路、键盘/显示接口电路及串行通讯接口电路等硬件部分的设计及相应的软件设计。由于DSP外围接口的逻辑控制繁多,使用CPLD作为DSP与其外围器件之间的接口,简化了系统的设计。本系统以离子敏场效应管为换能元件,并将DSP和CPLD相结合的技术应用到青霉素浓度测试系统。该系统能快速、准确地检测出青霉素的浓度。目前,国内外应用此类技术检测青霉素浓度的相关报道和文献较少,因此本文对后续研究工作具有一定的参考价值。更多还原

【Abstract】 Penicillin is widely used to prevent and cure cow’s diseases in veterinarian. However, if it is used frequently or over-quantity, there will be a certain quantity of penicillin left in milk. For milk is closely bound with everybody’s daily life, it must have influenced people’s health strongly if people drink milk containing rudimental penicillin for a long period. There are many traditional methods for detecting penicillin, but all of them have many disadvantages, such as long detecting time, fussy operation, low detecting precision, and high expense. Presently, biosensor is flourishing in the domains of electrochemistry and electro analysis chemistry, and it has been used in a good many aspects such as life sciences, environment sciences, analysis sciences, material sciences. Compared with the conventional detecting penicillin methods, biosensor is easier to realize the detection on the spot, due to its own merits such as fast detection, high sensitivity, better specialization, briefness and economy. Therefore, using ion-sensitivity field effect transistor (ISFET) as sensor and TMS320LF2407A as the control core, the system of detecting the penicillin concentration is designed.Because MOSFET and ISFET have similar structures, the traits of ISFET are analyzed in detail from the performance of MOSFET. Thereby the certain functional relation of penicillin concentration and electroencephalogram (EEG) could be gained. Based on the above the electricity current method to read EEG of the sensor is chosen. Using TMS320LF2407A as the control core, the periphery circuit of the detecting system is designed, including the design of hardware and software of magnify and filter circuit, A/D converter, memorizer expanded circuit, clavier-show interface circuit, serial communication interface circuit, etc. Owing to the various logic control of DSP periphery interface, CPLD is used as the interface of DSP and its periphery parts to simplify the design of the system. This system takes ISFET as transducer components, and applies DSP and CPLD to the system of detecting the penicillin concentration. And the system could detect the penicillin concentration quickly and exactly. At present, there are less correlative reports and literatures which adopt this technology to detect the penicillin concentration. Therefore, this article is valuable to the coming study work.更多还原