【作者】 刘建成；

【导师】 黄一帆；

【作者基本信息】 福建农林大学 ， 临床兽医学， 2004， 硕士

【摘要】 选用45头平均体重为10kg左右的杜长大三元杂交断奶仔猪进行试验。试验分3组，通过在基础日粮中分别添加研制加工成的中药饲料添加剂Ⅰ、Ⅱ号（称中药Ⅰ、Ⅱ组）和抗生素等化学合成药物，比较它们之间对猪体生长性能（日增重等）、腹泻率及血液生化、免疫机能指标（IgG、IgM、IgA、总蛋白、白蛋白、补体3、补体4、IL-2、淋巴细胞阳性率等）等的影响。全程试验分10—20kg、20—40kg、40—70kg、70—90kg四个阶段，中药Ⅰ、Ⅱ组与对照组相比，生长性能结果如下：中药Ⅰ组日增重分别提高了6.54％、5.01％、4.49％和4.74％，料重比分别降低了1.55％、8.25％、5.65％和-0.03％；中药Ⅱ组日增重分别提高了1.44％、2.24％、4.12％和4.55％，料重比分别降低了-2.50％、6.01％、6.21％和1.08％，且两个中药处理组还能有效防止10—40kg阶段猪只发生腹泻。在10—20kg、20—40kg、40—65kg三个阶段，中药试验Ⅰ组、Ⅱ组与对照组相比，血液生化及免疫机能指标方面结果如下：血清IgG水平，分别提高了10.15％（P＜0.05），18.06％（P＜0.01），12.28％（P＜0.01）；8.07％（P＜0.05），9.47％（P＜0.05），6.71％（P＜0.05）。IgM水平，分别提高了11.37％（P＜0.05），10.78％（P＜0.05），11.83％（P＜0.05）：5.88％（P＞0.05），9.95％（P＜0.05），9.67％（P＜0.05）。IgA水平，分别提高了2.82％（P＞0.05），9.97％（P＜0.05）9.21％（P＜0.05）；1.69％（P＞0.05），8.39％（P＜0.05），7.89％（P＜0.05）。总蛋白水平，分别提高了16.05％（P＜0.01），10.92％（P＜0.01），22.38％（P＜0.01）；8.90％（P＜0.05），6.85％（P＜0.05），15.57％（P＜0.05）。白蛋白水平，分别提高了18.23％（P＜0.05），20.34％（P＜0.01），21.69％（P＜0.05）；8.90％（P＞0.05），10.39％（P＜0.05），9.28％（P＞0.05）。血清C₃含量分别提高了17.56％（P＜0.05），22.32％（P＜0.05），16.53％（P＞0.05）；12.56％（P＜0.05），11.16％（P＞0.05），9.83％（P＞0.05）。血清C₄含量分别提高了42.11％（P＞0.05），59.09％（P＜0.05），56.47％（P＜0.01）；31.58％（P＞0.05），54.55％（P＜0.05），38.82％（P＜0.05）。血清IL-2含量分别提高了8.66％（P＜0.05），6.93％（P＜0.05），9.36％（P＜0.01）；5.80％（P＞0.05），6.02％（P＞0.05），6.29％（P＜0.05）。在猪只20—40Kg阶段，与对照组相比，中药Ⅰ组、Ⅱ组的T淋巴细胞（ANAE）阳性 福建农林大学硕士论文率水平，分别提高了6.56%（P>0.05）和2.1叽（p>0.05）。 试验结果表明，中药饲料添加剂I、n号的应用，与对照组比较，可以显著提高肉猪的生长性能;显著影响血液生化指标并明显提高猪只的免疫机能。试验还证实中药饲料添加剂在肉猪的促长、提高抗病力方面的作用相当并优于部分抗生素及化学合成药物。试验结果为中药饲料添加剂在药残控制无公害生猪生产的应用推广提供了科学理论依据。更多还原

【Abstract】 A total of 45 D*L*Y crossbred weaned piglets with average weight of about 10 Kg were selected and assigned to three groups. Two different kinds of Chinese herb feed additives(I and II) and antibiotic(chemical medicament) were supplemented respectively to 3 groups (Group I, Group II and Control Group ) to investigate the effects on the growing characteristics (i.e. daily weight gains, etc), diarrhea rate and biochemical quota of blood and function quota of immunity (IgG, IgM, IgA, Total protein, albumin,alexin3(C3), alexin4(C4), IL-2, positive ratio of T-lymphocytes). The whole feeding experiments divides into 4 stages, namely 10-20 Kg, 20-40 Kg, 40-70 Kg, 70-90 Kg. Compared with the Control Group, the results of the growing characteristics shows as follows:Daily weight gain in Group I increases by 6.54%,5.01%, 4.49% and 4.74% respectively in the four stages, while the feed conversion ratio decreases by 1.55%, 8.25%, 5.65% -0.03%respectively. Daily weight gain in Group II increases by 1.44%, 2.24%, 4.12% and 4.55% respectively, while the feed conversion ratio decreases by -2.50%> 6.01%> 6.21% 1.08%. The two treatment groups were found to be able to prevent piglets weighing 10-40 Kg from diarrhea effectively. Compared with the Control Group, in the stage of 10-20 Kg, 20-40 Kg, 40-70 Kg, Group I and Group II both get the blood biochemical quota and immunity function quota as follows: IgG of serum increases by 10.15% (PO.05) , 18.06% (P<0.01) and 12.28% (P<0.01) ; 8.07% (P<0.05), 9.47% (P<0.05) and 6.71% (P<0.05)o IgM increases by 11.37% (P<0.05), 10.78% (P>.05) and 11.83% (P<0.05); 5.88% (P<0.05), 9.95%(P<0.05) and 9.67% (P<0.05), IgA increases by 2.82% (P>.05) , 9.97% (P<0.05) and 9.21% (PO.05) ; 1.69% (P>.05), 8.39% (P<0.05) and 7.89% (P<0.05). Total protein increases by 16.05% (P<0.01) , 10.92% (P<0.01) and 22.38% (P<0.01) ; 8.90% (P<0.05), 6.85% (P<0.05) and 15.57%(P<0.05). Albumin increases by 18.23% (PO.05) , 20.34% (P>.01) and 21.69% (P<0.05) ; 8.90% (P>.05), 10.39%(P<0.05) and 9.28% (P>.05)? C3 of serum increases by 17.56% (P<0.05) , 22.32% (P<0.05) and 16.53% (P>.05); 12.56% (P<0.05), 11.16% (P>.05)and 9.83% (P>.05). C4of serum increases by 42.11% (P>0.05) , 59.09% (P<0.05) and 56.47% (P<0.01) : 31.58% (P>.05), 54.55% (P<0.05) and 38.82% (P<0.05). IL-2 increases by 8.66% (PO.05) , 6.93% (PO.05) and 9.36% (P<0.01) ; 5.80% (P>.05), 6.02% (P>.05)and 6.29% (P<0.05). During the growth stage of 20-40 Kg, compared with the Control Group, the positive rate of T-lymphocytes in Group I and Group II increases by 6.56% (P>0.05) and 2.19% (P>0.05) respectively.The results indicated that compared with Control Group, the supplement of Chinese herb feed additives I and n can improve obviously the piglets’ the growing characteristics, effect the blood biochemical quota noticeably , thus upgrade the immunity function of piglets. It is also proved that the supplement of Chinese herb feed additives is equivalent or superior to parts of antibiotic (chemical medicament) in terms of the growth promotion, disease resistance. It provides the scientific theory basis for the popularizing applications of Chinese herb feed additives in porker production of non-environmental pollution and control of residues of medicine.更多还原