【作者】 孔祥勇；

【导师】 张甦颖；

【作者基本信息】 山东中医药大学 ， 中医临床基础， 2003， 硕士

【摘要】 目的：对通腑降浊法治疗急性缺血性脑卒中急性期的机理及应用前景作了初步探讨，以期为该病的中医药治疗提供新的思路和有效方药。方法：通过查阅大量古今文献资料，结合缺血性脑卒中急性期的病机演变规律和中医脏腑相关理论以及临床辨证特色，认为该病的基本病机为痰瘀互结，腑气不通，络脉痹阻，且尤以腑气不通为关键。据此组方通腑降浊汤治疗缺血性脑卒中急性期30例，并与尼可林、脑复康组作对照。10天为一疗程，治疗两个疗程后，进行临床疗效与血液流变学指标的观察。结果：实验组总有效率为96.33％；对照组总有效率为76.67％。两组比较，具有显著性差别(P＜0.05)；在改善症状及血液流变学方面，治疗组明显优于对照组。结论：本研究通过理论探讨与临床实践的有机结合，深化了中医学对缺血性脑卒中急性期病因病机的认识，也进一步丰富了该病的治则治法，因而具有重要的理论意义和实用价值。更多还原

【Abstract】 Objective: To explore elementarily the mechanism and the applied foreground of treating the acute stage of cerebral ischemic stroke (CIS) with a therapy of dredging Qi of Fu-organ and subsiding reverse, and to provide a new idea and effective therapy of treating the acute stage of cerebral ischemic stroke with Chinese herbs. Method. Based on consulting lots of Chinese and foreign documentation, we think that the main mechanism of the acute stage of cerebral ischemic stroke is attributed to obstruction of Qi of Fu-organ, phlegm and hemostasis. So obstruction of Qi of Fu-organ is very important. On the grounds of it, we set down the decoction of Tong-Fu-Jiang-Zhuo. 60 cases with CIS are divided into two groups randomly. Then the decoction of Tong-Fu-Jiang-Zhuo is given to the experiment group, while Citicolinum and Piracetam is given to the control group. One period of treatment is for ten days. After two periods of treatment, the curative effect and some guidelines of blood stream are observed. Results: The totally effective rate of experiment group is 96.33%; and compared to that of control group is 76.67%.There is a significant difference between them(P<0.05).Conclusions: Through combined theory-study and clinical experiments, we’ve had better understanding of the pathogen and mechanism of the acute stage of CIS, and enriched the therapy of the acute stage of CIS. So the article is of great significance both in theory and clinic practice. Thus therapy of Tong-Fu-Jiang-Zhuo can be widely used in the clinical treatment.更多还原