【作者】 孙晓；

【导师】 李东燕；

【作者基本信息】 兰州大学 ， 神经病学， 2013， 硕士

【摘要】 目的：根据卫生部脑卒中筛查项目分析脑卒中及颈动脉粥样硬化性狭窄的危险因素,为我院脑卒中的筛查提供更全面的标准。方法：1、160例样本来自2010年12月-2012年3月在甘肃省人民医院神经内科住院且符合卫生部规定的脑卒中筛查标准并进行脑卒中筛查的患者,男72例,女88例,年龄≥40岁,平均(60±7.23)岁。2、收集临床资料并填写“脑卒中高危人群风险初筛评估简表”,再进一步进行体格检查,实验室检查,颈部血管超声检查。3、危险因素分析采用SPSS19.0统计软件进行分析。结果：1、男性,年龄>40岁,血脂代谢异常,牙周疾病,高同型半胱氨酸血症和高纤维蛋白原血症是颈动脉粥样硬化性狭窄的危险因素。2、颈动脉粥样硬化性狭窄的程度越重血浆同型半胱氨酸和纤维蛋白原的含量越高。结论：1、积极预防血脂代谢异常,牙周疾病,高同型半胱氨酸血症和高纤维蛋白原血症可以在一定程度上延缓颈动脉粥样硬化的发生。2、在卫生部规定的脑卒中筛查基本项目中增加血浆同型半胱氨酸及纤维货白原含量的检测可以及时预防Hcy和Fib的升高,为预防颈动脉粥样硬化的形成提供科学依据。更多还原

【Abstract】 Objective:To analysis the risk factors for carotid atherosclerotic stenosis by the screening for stroke which was put forward by Ministry of Public Health,and provide more overall screen contents for screening of stroke.Methods:1.160samples who were from neurology patients in our hospital from december2010to march2013.The160samples all fit for Screening standards and have been screened,72male patients,88female patiens, age≥40years old, mean age60±7.23years.2.Fist,Collecting clinical data and fill in Basic stroke screening information table, medical examination: Second.carry on physical examination, laboratory investigation, cervical vascular ultrasonography for the patients.3.Factors were analyzed by SPSS16.0.Outcomes:1.Male, age≥40years old, abnormal lipid metabolism, Periodontal disease, hyperhomocysteinemia and high fibrinogen in blood are all the fctors of Carotid atherosclerotic stenosis.2.The degree of the stricture is more serious the level of Hcy and FIB are more high.Conclusion:1.Prevent abnormal lipid metabolism,Periodontal disease hyperhomocysteinemia and high fibrinogen in blood can postpone the occurrence of Carotid atherosclerotic stenosis in a way.2.Add the detection of the Hcy and Fib can prevent the increases of Hcy and Fib,to take precautions against Carotid atherosclerotic stenosis.更多还原