【作者】 裴高油；

【导师】 冯广森；

【作者基本信息】 郑州大学 ， 临床医学， 2012， 硕士

【摘要】 目的探讨血管内介入栓塞治疗颅内动脉瘤的疗效,总结临床经验并指导实践。方法采用MDS或GDC对108例颅内动脉瘤患者进行血管内介入栓塞治疗,观察近期、远期疗效,并进行疗效分析。结果完全栓塞98例(90.74%),不完全栓塞7例(6.48%),部分栓塞2例(1.85%),失败1例(0.93%)。发生并发症4例(3.70%)。术后3个月mRS评价,预后良好98例(90.74%),中度残疾5例(4.63%),重度残疾1例(0.93%),死亡4例(3.70%)。随访3-36个月,部分栓塞1例复发,再行GDC栓塞成功,其余未见复发,动脉瘤不复显影。血管内介入栓塞疗效随介入时机延迟和Hunt-Hess分级升高呈下降趋势,MDS与GDC栓塞无显著性差异。结论血管内介入栓塞是一种安全、可靠、有效的颅内动脉瘤治疗方法。更多还原

【Abstract】 ObjectiveTo investigate the efficacy of the intravascular interventional embolization on intracranial aneurysms, summarize the clinical experience and guide practice.MethodsThe MDS or GDC were used on108cases of patients with intravascular aneurysms to take intracranial interventional embolization, the recently, the long-term efficacy were observed, and analyzed the efficacy.Results98cases of complete embolization (90.74%),7cases of incomplete embolization (6.48%),2cases of partial embolization (1.85%), one cases was failure (0.93%). Complications occurred on4cases (3.70%). After3months took mRS evaluation,98cases had good prognosis (90.74%),5cases were moderate disability (4.63%),1cases was severe disability (0.93%),4patients died (3.70%). The patients were followed up for3to38months,1patients with partial embolization was recurrent, and with success by re-GDC embolization, the rest had no recurrence, the aneurysm was no longer developing. The efficacy of endovascular embolization showed a downward trend with intervention time delay and Hunt-Hess grade increases, the MDS and GDC embolization had no significant difference. ConclusionEndovascular interventional embolization is a safe, reliable and effective method to treat intracranial aneurysm, to obtain a good prognosis, the intervention time should be within3days after hemorrhage.更多还原