【作者】 张虹；

【导师】 陈波；

【作者基本信息】 黑龙江中医药大学 ， 中西医结合临床， 2011， 硕士

【摘要】 目的观察胸痹贴Ⅰ号对气虚血瘀型不稳定型心绞痛患者临床疗效以及CD40L的影响,分析揭示其对该病的治疗机制。方法60例气虚血瘀型不稳定型心绞痛患者随机分成对照组(西医基础治疗)和治疗组(西药基础治疗+胸痹贴Ⅰ号),每组各30例,治疗两周,观察疗前疗后CD40L的变化、西雅图心绞痛量表评分等指标。结果1.两组CD40L均较疗前有所降低(P<0.05)。2.与对照组相比,治疗组降低血小板CD40L更明显(P<0.05)。3.两组心绞痛量表评分均有提高(P<0.05)。4.与对照组相比,治疗组心绞痛量表评分提高更明显(P<0.05)。结论1.胸痹贴Ⅰ号能够有效降低外周血中CD40L的含量。2.胸痹贴Ⅰ号可以提高西雅图心绞痛量表的各项评分,表明该药贴可以提高病人生活质量及改善机体功能状态。更多还原

【Abstract】 Objective To observe the effect of the xiongbitie-I on the clinical treatment of UA and the expression of CD40L and analysis the mechanism of its treatment on UA.Methods 60 patients with unstable angina pectoris were randomly divided into 2 groups. The treatment group and the control group both have 30 patients. There is no obvious difference in age、sex、illness course and severity degree between the two groups. Observe the change of the level of CD40L and the curative effect of unstable angina pectoris.Results 1. The level of CD40L in both groups reduced (p< 0.05) 2. The level of CD40L in treatment group reduced more obviously than the control group 3.xiongbitie-Ⅰhas a obvious curative effect.Conclusion 1.xiongbitie-Ⅰcould depress the level of CD40L in blood.2. xiongbitie-Ⅰcould improve the quality of life and the functional status of patients.更多还原