【作者】 曲岩；

【导师】 陈少宗；

【作者基本信息】 山东中医药大学 ， 针灸推拿学， 2011， 硕士

【摘要】 目的:对清华同方全文期刊数据库(CNKI) 1979年1月～2010年12月之间和重庆维普中文期刊数据库(VIP) 1989年～2010年之间发表的穴位贴敷治疗支气管哮喘的临床治疗性RCT文献进行循证评价。方法:检索1979年1月—2010年12月间的穴位贴敷治疗支气管哮喘临床治疗性RCT文献,将符合纳入标准的文献进行信息采集和质量评价。用Microsoft Access 2000建立数据库,进行数据的录入和管理。采用Cochrane协作网提供的RevMan4.2版对数据归类合并,进行Meta分析。结果:在纳入的50篇穴位贴敷治疗支气管哮喘的随机对照研究中,49篇临床研究文献有人口学特征描述,47篇进行了组间均衡性比较,8篇采用随机数字表随机分组,1篇研究采用抛硬币法随机分组,4个研究为半随机对照试验。只有1篇文献提及随机方案隐藏,6篇提及盲法。12篇文献提及随访,15篇提及不良反应,3篇文献提及病例脱落情况,1篇提及病例剔除情况。50篇文献均进行了统计学处理,27篇描述了具体统计方法。治疗结果的Meta分析显示:穴位贴敷组与药物对照组在总体效应上有非常明显的差异,敏感性分析表明此结论比较稳定可靠;在常规治疗基础上加用穴位贴敷的疗效优于单纯常规治疗;穴位贴敷组与针刺治疗组在总体效应上没有非常明显的差异。结论:研究显示穴位贴敷治疗支气管哮喘比药物对照和空白对照更为有效,与针刺治疗疗效相差不大,但纳入文献质量普遍偏低,下一步研究尚需更多高质量的随机对照试验的文献。更多还原

【Abstract】 Purpose: Evaluate the RCT literatures on treating bronchial asthma with point application published between 1979 Jaurary and 2010 December. Methods: Retrieve the RCT literatures on treating bronchial asthma with point application published between 1979 Jaurary and 2010 December and establish the database with Microsoft Access 2000, then Meta analysis. Result: Of all the 50 included studies, there are 49 descripted demographic characteristics, 47 comparied the balance between groups, 8 randomized by random number table and 1 by flipping a coin, 4 are quasi-randomised controlled trials. There is only 1 literature mentions random scheme hidden, 2 mention blinding. There are 12 literatures mention follow-up visit, 15 mention adverse reaction, 3 mention dropout and 1 mentions elimination. All the researches analysed statistically and 27 of them descripted the specific statistic method. Meta analysis shows that there is significant statistical difference on clinical effect between point application and drug theropy, and this conclusion is stable and reliable according to sensitivity analysis, the conventional treatment combined with point application has a better effectiveness, there is no statistical difference on clinical effect between point application and acupuncture. Conclusion: The study shows that point application has a better effectiveness than drug, and there is no statistical difference between point application and acupuncture. Yet the included researches have general low quality, researches of high quality is needed.更多还原