【作者】 胡登科；

【导师】 杨昆胜；

【作者基本信息】 昆明医学院 ， 神经病学， 2011， 硕士

【摘要】 目的探讨急性脑梗塞并发肺部感染相关的诱发机制及影响因素,以便有效的预防和控制肺部感染的发生。方法通过回顾性分析2007年1月至2009年2月我科收治的1100例急性脑梗塞患者,其中并发肺部感染188例的流行病学资料、既往史、病情严重程度、治疗及预后,再具体分析肺部感染的发生率与患者性别、年龄、吸烟饮酒史、慢性基础病、梗塞程度、意识状态、吞咽功能、侵袭性操作、预防性抗感染治疗及预后的关系。结果男性、高龄、既往合并有卒中及肺部疾患者、梗塞面积大、昏迷者、存在吞咽功能障碍和侵袭性操作的患者肺部感染发生率明显增高。吸烟饮酒史、预防性抗感染治疗与急性脑梗塞后合并肺部感染的发生无显著关系。合并肺部感染的脑梗塞患者病死率明显高于无肺部感染者。结论预防和控制肺部感染可有效提高急性脑梗塞的救治成功率并可改善预后。更多还原

【Abstract】 Subject:In order to prevent and control the occurrence of pulmonary infection effectively, we investigate the evoking mechanisms and influencing factors in patients with acute cerebral infarction complicated with pulmonary infection.Methods:We investigate the epidemiological information, history of past illness, seriousness degree of diseases, treatment and prognosis of 1100 acute cerebral infarction cases in our department from January, 2007 to February,2009, including 188 cases complicated with pulmonary infection. Then we analysis the relationship between pulmonary infection rate and gender, age, smoking and drinking histories, basic chronic diseases and illness degree, infarction degree, state of consciousness, swallowing function, invasive operation, preventive anti-infection therapy, prognosis of the patients.Results:The pulmonary infection rate increased obviously in patient who is male, aged, associated with stroke and lung diseases, accepting invasive operation and has severe illness, coma, swallowing dysphagia. Smoking and drinking histories, preventive anti-infection therapy and acute cerebral infarction lung infections had no significant relationship. Patients with cerebral infarction complicated pulmonary infections have obviously higher fatality than patients without lung infection.Conclusion:Preventing and controlling pulmonary infection can effectively improve the treatment and prognosis of acute cerebral infarction.更多还原