【作者】 卞炜；

【导师】 胡幼平；

【作者基本信息】 成都中医药大学 ， 针灸推拿学， 2010， 硕士

【摘要】 目的：采用多中心随机对照临床试验,观察围刺加电针疗法治疗带状疱疹(AHZ)的临床疗效。方法：采用多中心、随机对照试验的研究方法,共62例患者纳入并完成研究,随机分为治疗组(32例)和对照组(30例)。其中剔除病例4例,58例病人完成整个研究过程并纳入分析。治疗组采用围刺加电针治疗,对照组采用西药治疗。每天观察一次疗效,记录带状疱疹综合疗效评分、疱疹情况、疼痛情况,治疗结束后进行疗效评价。结果：(1)两组的基线状况良好,分组均衡,可比性较强(P＞0.05)。(2)治疗组的总有效率为96.67%。治疗组的疗效,总有效率与对照组相比,差异无统计学意义(P＞0.05)。(3)治疗组疼痛VAS评分的自身前后对照,治疗后组间对照,治疗组较对照组有显著性差异(P<0.05)。(4)治疗组局部疼痛评分自身前后对照,治疗后组间对照,治疗组较对照组有显著性差异(P<0.05)。(5)治疗组第30天随访后遗神经痛发生率较对照组有显著性差异(P<0.05)。结论：(1)围刺加电针疗法对带状疱疹具有良好的疗效,在改善患者VAS评分、疼痛持续时间、局部疼痛和控制30天后遗神经痛方面优于西药疗法。(2)针刺疗法不良反应少,安全性好。(3)针刺疗法操作简单,成本低廉,疗效好,适宜临床运用推广。更多还原

【Abstract】 Object:This study was based on multi-center randomized controlled traial,to examine the effect of surrounding acupuncture plus electro-acupuncture for treating acute herpes zoster (AHZ).Method:With a multi-center randomized, single-blind and controlled trial, a total of 62 patients included in this study were randomly divided into experimental group (32 cases) and controlled group (30 cases), which four were rejected, leaving 58 finished the whole study and been accounted into the final analysis. Experimental group was given surrounding acupuncture plus electro-acupuncture during observation while its counterpart was prescribed by western medicines. The effect of either group was checked daily. Scores of general effect assessment on AHZ, herpes syndrome as well as pain were recorded, and the effects of both groups were assessed upon completion of the treatment.Result:(1). the baseline condition in either group was fine and balanced with reasonable compatibility (P>0.05); (2). the total effective rate in experimental group was 96.67%, and the total effective rate in both groups has no statistically significant difference (P>0.05); (3), the after-treatment score of the pain VAS assessment in experimental group has statistical significance comparing with that of before-treatment, and post treatment pain VAS scores between groups showed better result with statistical significance in the experimental group than that of the controlled group (P<0.05); (4), the local pain score of experimental group after treatment was with statistical significance compared with that of before treatment, and post-treatment local pain scores between groups showed statistical significance with better result in the experimental group (P<0.05); and (5), recurrence rate of postherpetic neuralgia (PHN) in the experimental group was statistically significant in contrast with that of the controlled group on the 30th day follow-up observation (P<0.05).Conclusion:First, the combination of surrounding acupuncture with electro-acupuncture shows better effect for treating AHZ and is better over western medicine in terms of improving VAS scores for patients, shorting pain duration, relieving local pain as well as restraining postherpetic neuralgia after 30 days. Second, acupuncture demonstrates fewer adverse events and better safety. Third, simple manipulation, cheap cost and good effectiveness of acupuncture makes it suitable to popularize and practice in clinics.更多还原