【作者】 韩佳佳；

【导师】 叶青；

【作者基本信息】 山东中医药大学 ， 中医妇科学， 2010， 硕士

【摘要】 目的：观察益气固冲化瘀法分期治疗气虚血瘀型围绝经期无排卵性功血的临床疗效并探讨其止血和调经机理。方法：共观察60例气虚血瘀型围绝经期无排卵性功血患者,随机分为治疗组30例(出血期口服参芪固冲止血方,血止后口服参芪固冲调经方),对照组30例(出血期口服致康胶囊,血止后口服补中益气颗粒),观察两组患者的止血疗效、中药调整月经综合疗效、中医主要症状改善情况,同时观察治疗前后子宫内膜厚度和血红蛋白的变化情况。结果：治疗组与对照组近期止血疗效总有效率分别为：90%、56.67%,两者相比有非常显著性差异(P<0.01)；治疗后两组中医单项症状积分和总积分组间比较有显著性差异(P<0.05)；治疗后治疗组患者的子宫内膜厚度较前明显降低,血红蛋白的含量明显升高,与治疗前相比有非常显著性差异(P<0.01),与对照组相比有显著性差异(P<0.05)；治疗后治疗组综合疗效为93.33%,对照组为73.33%,组间比较有非常显著性差异(P<0.01)。结论：益气固冲化瘀法对气虚血瘀型围绝经期无排卵性功血具有较好的止血疗效和调整月经综合疗效,并能显著改善患者的气虚血瘀证候。更多还原

【Abstract】 Objective:To observe the clinical effect of Yiqi Guchong Huayu method in treating hemorrhagic period of perimenopausal anovulatory dysfunctional uterine bleeding with qi deficiency and blood stagnation syndrome,and to explore its hemostasis and menstrual cycle adjusting mechanism. Methods:60 patients were divided into two groups randomly, 30 cases of the treatment group using shenqi guchongzhixue fang ang shenqi guchong tiaojing fang while 30 cases of the control group using Zhikang Capsule(ZKC) and Buzhongyiqi Granule.To observe the changes hemostatic effect and menstrual cycle adjusting effect, the improvements of clinical symptoms, the thickness of endometrium, and the change of hemoglobin(Hb). Results:The hemoistatic effect of treament group is 90%,and 56.67% in control group,there is significant difference between them(P<0.01);the single and total symptoms score of the clinical symptoms are difference between them (P<0.05);Significant difference was shown in decreasing the thickness of endometrium and improving Hb,when compared with before treatment (P<0.01), the difference is also significant compared with control group (P<0.05);the total effective rate in adjusting menstrual cycle of treament group is 93.33%,and 73.33% in control group, there is significant difference between them(P<0.01). Conclusion:Yi-Qi-Gu-Chong-Hua-Yu method has favourable hemoistatic and menstrual cycle adjusting effects in treating hemorrhagic period of perimenopausal anovulatory dysfunctional uterine bleeding with qi deficiency and Blood stagnatio syndrome,and it also can improve the accompanied clinical symptoms significantly.更多还原