【摘要】 目的:对赴汶川地区执行抗震救灾任务的医护人员免疫功能进行评估。方法:对某部95名医护人员血液学指标和T、B、NK淋巴细胞亚群等6项免疫参数进行测定,并按年龄、性别及工作环境危险程度分组,进行统计学相关分析。结果:按距离震源由远及近依次分为A(成都)、B(都江堰)和C(水磨)三组,其危险程度A组<B组<C组。A组和B组CD3+T淋巴细胞显著低于C组(P<0.05),其他指标无明显变化;B组淋巴细胞计数绝对值显著低于C组(P<0.05)。女性组CD3+CD4+T淋巴细胞显著高于男性组(P<0.05),CD4/CD8比值显著高于男性组(P<0.05)。年龄对免疫功能无影响。结论:环境对参加抗震救灾医护人员淋巴细胞绝对值计数和CD3+T总淋巴细胞有一定影响,且女性免疫力明显高于男性。更多还原

【Abstract】 Objective: To evaluate immune function of 95 medical team members who have taken part in earthquake relief work in Wenchuan.Methods: The hematological parameters and percentage of T,B,NK cell subpopulations from peripheral blood of 95 medical members were measured by automatic blood analyzer and flow cytometry,and they were divided into different groups by age and different work environments.The statistic analysis have been done by different groups.Results: According to the distance to seimic origin from far to near,the medical team were divided into 3 groups,which were named as group A(Chengdu),group B(Dujiangyan) and group C(Shuimo).The percentage of CD3+T cells with group A and group B were lower than that with group C(P<0.05).The absolute value count of lymphocytes in group B was significantly lower than that in group C(P<0.05).The percentage of CD3+CD4+ T lymphocytes in female group was significantly higher than that of male group by different sex(P<0.05),and the value of CD4/CD8 in female group was higher than that of male group(P<0.05).Age had no effect on immune function of 95 medical team members.Conclusion: Environment have a certain impact on the absolute count of lymphocyte and the percentage of CD3+ T lymphocytes of medical team members,and immune function of women is significantly higher than that of men in this earthquake relief.更多还原