【作者】 陈燕云；

【导师】 黄泳；

【作者基本信息】 南方医科大学 ， 中西医结合临床， 2011， 博士

【摘要】 目的：观察运用薄氏腹针配合体针与单纯运用体针治疗轻中度抑郁症的临床疗效。方法：临床观察于2009.10-2010.5在香港健宝、天佑堂、昊域、良方等中医诊所完成。将62例轻中度抑郁症患者随机分为薄氏腹针配合体针治疗组(治疗组)和体针治疗组(对照组)。观察周期为1个疗程(28天)。观察指标包括临床疗效、治疗前后汉密尔顿(Hamilton)抑郁量表(HAMD)-17项总分、各因子分值和Zung抑郁自评量表(SDS)测评,治疗过程中患者不适记录等。结果：治疗组31例轻中度抑郁症患者,痊愈1例,显进步18例,进步11例,无效1例,总有效率96.77%；对照组31例轻中度抑郁症患者,痊愈0例,显进步7例,进步19例,无效5例,总有效率83.87%；Wilcoxon秩和检验发现治疗组的综合疗效显著优于对照组(Z=3.225,P=0.001)。配对t检验发现,两组患者治疗后HAMD-17项量表总分、SDS量表评分和焦虑／躯体化均显著低于治疗前(P<0.05)；经Wilcoxon符号秩和检验,得出阻滞、睡眠障碍和体重因子分值也显著低于治疗前。通过两组患者各指标下降值的比较,得出治疗组治疗后的HAMD-17项量表总分、SDS量表评分、阻滞评分和睡眠障碍评分与对照组比较均具有显著性差异(P<0.05),而两组治疗后的焦虑躯体化和体重评分比较无显著性差异(P>0.05)。结论：薄氏腹针配合体针疗法和体针疗法均能明显减低轻中度抑郁症患者的HAMD-17项量表评分和SDS量表评分,改善轻中度抑郁症患者的焦虑、阻滞、睡眠障碍等症状,且薄氏腹针配合体针疗法对轻中度抑郁症的干预治疗作用优于体针疗法。更多还原

【Abstract】 Object:Observed the curative effect of applying Bo’s Abdominal Acupuncture combined with Body Acupuncture to treat mild to moderate clinical depression.Method:Clinical observation was completed in Jian Bao,Tian Youtang, Hao Yu, Liang Fang and other traditional Chinese medicine clinics of Hongkong from October, 2009 to May,2010.62 patients with mild and midrange depression were randomly divided into treatment group (abdominal acupuncture combined with body acupuncture group) and control group (body acupuncture group). Observation period was one treatment course (28 days). Observations included curative effect, assesements of Hamilton Rating Scale for depression (HAMD-17 item) and Zung Self-Rating Depression Scale (SDS) before and after the treatmentResults: Among 31 patients with mild to moderate depression in treatment group,1 case got recovered,18 cases got significant improvement,11 cases got improvement, and 1 case got noneffectiveness, with the total effective rate of 96.77%; Among 31 patients in control group,0 case got recovered,7 cases got significant improvement, 19 cases got improvement, and 5 case got noneffectiveness, with the total effective rate of 83.87%; Wilcoxon rank sum test found that the general curative effect of the treatment group was significantly better than the control group (Z= 3.225, P= 0.001). Paired t test showed that after treatment the two groups’ HAMD scores, the SDS scale scores and the sub-factors of anxiety/somatization were significantly lower than that of before treatment (P<0.05). The Wilcoxon signed rank sum test showed that hysteresis, dyssomna and weight factor scores were significantly lower than before treatment (P<0.05). Comparison of two group’s various targets drop value showed that after treatment, the HAMD-17 item scale total score, SDS scale score, hysteresis and dyssomna scores compared with the control group were significant differences (P<0.05), the anxiety/somatization and the weight of the two groups after treatment was no significant difference (P>0.05).Conclusion:Both of Bo’s abdominal acupuncture combined with body acupuncture and body acupuncture could obviously decrease the scores of the HAMD-17 and SDS, and significantly improve the depressive symptoms, which was superior to body acupuncture.更多还原