【作者】 曾飞；

【导师】 高伟； 王晓峰；

【作者基本信息】 新疆医科大学 ， 中西医结合临床， 2010， 硕士

【摘要】 目的:评价芪红颗粒改善非体外循环心脏不停跳下冠脉搭桥术(OPCAB)后患者生存质量的临床观察。方法:将60例非体外循环下心脏不停跳冠脉搭桥术后患者随机分为两组,其中治疗组(30例)在西医冠脉搭桥术后常规治疗基础上加用芪红颗粒治疗,对照组(30例)采用西医冠脉搭桥术后常规治疗,比较2个月后两组用药前后中医临床症状疗效评分及心脏功能分级、心功能指标、西雅图心绞痛量表(SAQ)量化评分的改变。结果:两组均治疗2个月后,到达治疗终点,包括胸闷、胸痛、心悸、气短、自汗等(P<0.01) ;症状总评分试验组较对照组有改善明显(P<0.01),且治疗组的心脏功能分级的改善较对照组的明显,差异具有显著性(P<0.05),且治疗组治疗后左心室射血分数(LVEF)与左心室舒末前后径(LVEDD)有较为显著的改善(P<0.05),与对照组比较,有显著统计学差异(P<0.05)。治疗后组间比较显示,心绞痛稳定状态(anginal stability, AS)、心绞痛发作情况(anginal frequency, AF)、治疗满意程度(treatment satisfaction, TS)及总评分均高于对照组,差异有统计学意义(P<0.01或P<0.05)。结论:芪红颗粒配合西医常规治疗对非体外循环心脏不停跳下冠脉搭桥术(OPCAB)后患者生存质量有较明显的改善作用。更多还原

【Abstract】 Objective:To evaluate the clinical Observation of QiHong KeLi for raising the quality of life in patients with off-pump coronary artery bypass grafting (OPCAB)Methods : 60 patients off-pump coronary artery bypass grafting patients were allocated in treatment group (n=30)and control group(n=30). The treatment group (n=30) treated with conventional method of western medicine and qihong ke li ,The control group(n=30) treated with conventional method of western medicine, comparing the change of function of heart , heart function indexes and SAQ indexes in the two groups after therapy for two months.Result: After being treated for 2 months, Scoring of traditional medical symptoms in treatment group were significantly higher than those in the control group (P<0.05 ).the improvement of heart function were superior to those in the control group (P<0·05) respectively, after therapy the LVEF and LVEDD of the TCM-treated group (P<0.05)was significantly improved, comparing with the control group. The scores in terms of The scores in terms of anginal stability, anginal frequency、treatment satisfaction of patients in the experimental group according to SAQ scale were significantly higher than those in the control group (P<0.01或P<0.05 ).Conclusion: The improvement of quality of life is significantly with treatment group of qihong keli and conventional therapy in patients with off-pump coronary artery bypass grafting.更多还原