【作者】 李秋云；

【导师】 肖恩华；

【作者基本信息】 中南大学 ， 影像医学与核医学， 2010， 硕士

【摘要】 目的探索肝脏磁敏感成像(SWI)最佳扫描参数。方法对20名成年健康志愿者行肝脏SWI,比较不同磁敏感编码因子(SENSE)及激励次数(NEX)对图象质量的影响。SENSE因子分别取1、1.5、2.5、3.5,NEX分别取l、2、3。结果在不同参数的比较中,SENSE因子为1.5的图象质量较好,NEX为l的图象质量较好。结论SENSE为1.5、NEX为1是肝脏SWI较好的扫描参数。目的探讨磁敏感加权成像(SWI)在肝脏局灶性病变内部结构的显示能力及其鉴别诊断中的应用价值。方法搜集18例经临床及影像证实肝脏病变包括血管畸形、肝细胞癌、转移瘤、血管瘤以及肝囊肿患者共25个肝局灶性病变行常规T1WI、T2WI及SWI扫描。18例均同时行增强扫描,1例动静脉畸形同时行MRA检查,1例血管瘤动态增强后再次行SWI检查。结果1例血管畸形SWI能较常规平扫、增强及3DMRA更清楚显示其异常静脉血管形态；4例肝细胞癌、3例胆管细胞癌及2例转移瘤,SWI均能显示病灶内瘤静脉及血液降解产物；5例肝血管瘤及3例肝囊肿,SWI均显示病灶呈均匀稍高信号,病灶较大者邻近静脉受压。结论SWI在显示肝脏静脉性血管畸形、肿瘤相关静脉结构等方面优于常规MR序列,对肝脏局灶性病变有一定鉴别诊断价值,是研究肝脏局灶性病变内部结构的一种新的方法。更多还原

【Abstract】 Objective To evaluate parameters of susceptibility weighted imaging in the liver.Methods SWI of the liver was performed in 20 healthy adult volunteers. Different parameters include SENSE factor and number of excitation. SWI in liver was performed with different factor of SENSE including 1、1.5、2.5 and 3.5; and different number of excitation including 1、2、3.Results SWI with SENSE of 1.5 was better than that with 1、2.5 and 3.5. SWI with 1 excitation showed higher quality than that with 2 and 3.Conclusion SWI with SENSE factor 1.5 and 1 excitation was the better in SWI of the liver. Objective To investigate the value of susceptibility weighted imaging in discovery and diagnosis of focal liver lesions.Methods Eighteen patients with 25 focal liver lesions were collected,all of them were proved by diagnosis of clinic and imaging. It included liver vascular malformation (n=1),hepatocellular carcinoma (n =4), cholangiocellular carcinoma(n=3), metastatic tumor in liver(n=2), liver haemangioma (n=5), and liver cyst (n=3). MR imaging were performed with conventional T1WI, T2WI, SWI and dynamic Gd-DTPA contrast enhanced MRI.liver vascular malformation(n=1) performed 3DMRA and post-gadolinium enhanced SWI in one liver haemangioma was also obtained.Results:In liver Vascular malformation(n=1), SWI is better than conventional MRI and 3D-MRA in discovering anormally vein form. SWI could discover tumor vascular structure and degradation products of blood in hepatocellular carcinoma (n=4), cholangiocellular carcinoma (n=3) and metastatic tumor in liver(n=2). SWI showed uniformity slightly hypso-signal in liver haemangioma (n=5) and liver cyst (n=3), and in comparatively large lesion of which the neighbourhood vein was compressed. Conclusion:SWI was surpassed than conventional MRI sequences in discover liver venous Vascular malformation and vascular structure correlated in tumor. SWI is very helpful in differential diagnosis of focal liver lesions, It was a new approach to investigate the internal structures of focal liver lesions.更多还原