【作者】 康元元；

【导师】 孙正；

【作者基本信息】 华北电力大学（河北） ， 通信与信息系统， 2010， 硕士

【摘要】 X射线血管造影和血管内超声(IVUS)是目前临床普遍采用的诊断血管病变的介入性影像手段,二者具有优势与不足互补的特点。本文提出一种基于血管造影和IVUS图像融合的血管三维重建方法:首先从在两个近似垂直角度采集的造影图像中三维重建出导管路径和管腔轴线;然后沿三维导管路径确定各帧超声图像的轴向位置和空间方位;最后采用NURBS曲面拟合技术完成管腔内外表面的拟合。通过将血管造影提供的管腔和超声导管的空间几何信息以及从IVUS图像序列中获取的管腔横切面信息融合起来,得到感兴趣血管段的准确三维重建,辅助血管疾病特别是冠心病的诊治。本文的研究受到国家自然科学基金项目(编号:30500129和60973087)的资助。更多还原

【Abstract】 X-ray angiography and Intravascular Ultrasound (IVUS) are complementary interventional catheter based imaging modalities which are widely used in clinical diagnosis of vascular diseases. In this dissertation, a method for 3D reconstructing vessels based on fusion of angiographic and IVUS images is proposed. First, 3D vascular lumen axis and catheter pullback path is reconstructed from a pair of angiograms acquired from two nearly orthogonal views. Then, axial position and spatial orientation of each IVUS slice are determined along the 3D catheter path. Finally, fitting of inter and outer surface of the vessel lumen is implemented with the NURBS fitting technique. Vessels of interest are accurately reconstructed based on fusion of cross-sectional information of vessel lumen obtained from IVUS images and spatial geometrical information of catheter pullback path derived from angiograms to assist clinical diagnosis of vascular diseases especially coronary artery diseases.The research work in this dissertation was supported by National Nature Science Foundation of China (Grant Nos.30500129 and 60973087 ).更多还原