【作者】 丁宏；

【导师】 张浩；

【作者基本信息】 中国医科大学 ， 普通外科学， 2010， 硕士

【摘要】 目的研究急性胰腺炎与原发性甲状旁腺功能亢进的关系及以急性胰腺炎为临床表现的原发性甲状旁腺功能亢进的诊断与治疗。方法对收入我院的两例以急性胰腺炎为首发症状的原发性甲状旁腺功能亢进病例进行研究,结合以往国内外相关报告进行分析。结果两例患者均以“恶心、上腹痛”等消化道症状为主,且经相关检查与实验室检验均支持“急性胰腺炎”诊断。均按急性胰腺炎治疗无好转,并出现高钙危象后考虑可能为原发性甲状旁腺功能亢进。其中一例经调节血钙水平后接受手术治疗,预后良好；一例血钙调节不理想并出现心衰、呼衰抢救无效死亡。结论以急性胰腺炎为首发表现的原发性甲状旁腺功能亢进临床少见,容易误诊,应予重视；手术是治疗原发性甲状旁腺功能亢进的最直接有效方法。更多还原

【Abstract】 ObjectiveIn this article, we will discuss the relationship between acute pancreatitis and primary hyperparathyroidism and also we will learn the diagnosis and the treatment of the primary hyperparathyroidism which have the first presentation as acute pancreatitis.MethodsTwo cases of our hospital which shows the acute pancreatitis as the first presentation of primary hyperparathyroidism were studied and the similar literature were reviewed.ResultsBoth of the two cases had the chief complaint of vomiting and upper abdominal pain, related examination and blood test also supported the diagnosis of acute pancreatitis. But the patients’condition did not improve when they were treated as acute pancreatitis and high calcium crisis occured during the treatment when we started to think that there may be a consideration of primary hyperparathyroidism. One of the two patients, surgery was taken after the control of the value of blood calcium and showed a favourable prognosis; one died of congestive heart failure and respiratory failure without surgery for the value of blood calcium was not well controlled. ConclusionsAcute pancreatitis as the firs presentation of primary hyperparathyroidism which was rarely seen at clinical should be payed attention by us. Surgery is considered the most direct and effective way to cure primary hyperparah yroidism.更多还原