【作者】 徐沈杰；

【导师】 黄剑奇；

【作者基本信息】 浙江大学 ， 口腔医学， 2010， 硕士

【摘要】 目的：对组织细胞坏死性淋巴结炎进行临床分析,包括命名、发病情况、病因机制、临床表现、辅助检查、病理、诊断与鉴别诊断、治疗与预后。旨在提高对该病的认识,以提高临床诊治率。方法：结合所见临床病例,检索复习相关文献,分析组织细胞坏死性淋巴结炎各方面情况。结论：组织细胞坏死性淋巴结炎(HNL)又称坏死性淋巴结炎,病毒性淋巴结炎,亚急性淋巴结炎及KiKuchi Fujimoto病,由日本人Kikuchi和Fujimoto1972年首先报道并命名,是一种主要累及淋巴结的良性、自限性全身性疾病。病因不明,多发于东方青年女性。临床上表现为发热、浅表淋巴结肿大、皮疹等。由于在临床上缺乏特异性表现,且发病率较低,对该病认识不足,在口腔颌面外科的临床诊断中又难与其他淋巴结性疾病相鉴别,易导致误诊、误治。更多还原

【Abstract】 Objective:To analyze histiocytic necrotizing lymphadenitis (HNL),including the denominate, epidemiology, etiology, clinical manifestation, auxiliary examination, pathology, diagnosis and differential diagnosis, treatment and prognosis.Methods:Combining the repesentative case of histiocytic necrotizing lymphadenitis (HNL), search former literatures and analyze this disease.Conclusions:Histiocytic necrotizing lymphadenitis (HNL) is called necrotizing lymphadenitis, virus lymphadenitis, sub-acute lymphadenitis or Kikuchi Fujimoto Disease, which was first reported and denominated by Japanese Kikuchi and Fujimoto in 1972. It is benign, self-control, systematic disease which involves lymph nodes and often happens on young women in the east without clear etiology. Its manifest shows fever, lymphadenectasis, rash and so on. HNL is easily mistakenly treated for absence of specificity, low incidence rate, unfamiliarity with this disease and difficulty identification with other lymph nodes diseases.更多还原