【作者】 朱晓昱；

【导师】 许毅；

【作者基本信息】 浙江大学 ， 临床医学， 2010， 硕士

【摘要】 抑郁症(Depression)是一种以显著而持久的情绪低落为核心症状的精神疾患,具有高患病率、高复发率、高致残率和疾病负担沉重等特征。其病因复杂,涉及遗传、神经内分泌、生化、社会心理等多方面因素,临床伴随症状多,治疗时间长、根治难度大,是精神卫生领域的重要疾病之一。对于一些临床典型或特例的诊疗体会及时总结,有利于诊治的个体化,规范治疗方案。本文报道浙江大学医学院附属第一医院就诊的三例病人的诊断治疗过程并综述5-HTT基因多态性与抑郁症及其治疗关系的研究进展。更多还原

【Abstract】 Depression is a kind of mood disorders with the core symptoms of significant and lasting depression, with a high prevalence rate, high recurrence rate, high rate of disability and disease burden. The causes are complex and involve genetic, neuroendocrine, biochemical, psychosocial and other factors. The clinical symptoms varied and long course of treatment is needed. The difficulties in curing make depression an important field of mental diseases. To diagnose, take treatment and consultation in time for some special cases and summing up the clinical experience would be beneficial to carry out individual and standard treatment. This paper reported the process of diagnosis and treatment of 3 cases in The First Affiliated Hospital of clinical medicine college of Zhejiang University, and reviewed the relationship between 5-HTT gene polymorphism and the treatment of depression.更多还原