【作者】 董冰冰；

【导师】 范薇；

【作者基本信息】 长春理工大学 ， 无机化学， 2010， 硕士

【摘要】 本论文采用液相沉淀法合成了稀土席夫碱8-羟基喹啉配合物并对其抑菌性能进行了详细的研究。首先以水杨醛和5-氨基水杨酸为原料,合成配体席夫碱水杨醛缩5-氨基水杨酸,再以稀土氯化物(分别为轻稀土La、Nd,中稀土Gd、Tb,重稀土Yb)、席夫碱水杨醛缩5-氨基水杨酸和8-羟基喹啉为配体,在无水乙醇溶液中反应,制备出一类稀土新型三元配合物。通过核磁共振、红外光谱、紫外-可见吸收光谱、差热-热重分析等测试分析方法确定了所制备配合物的化学组成、性质和成键特性。配体席夫碱水杨醛缩5-氨基水杨酸以四齿形式参与配位,配体8-羟基喹啉以二齿形式参与配位,配位数分别为7(La和Nd)和9(Gd、Tb和Yb)。通过抗菌实验对所制备的稀土新型三元配合物的抑菌效果进行了研究,结果表明,配合物对大肠杆菌、枯草杆菌和青霉菌均表现出不同程度的抑菌效果,其中对枯草杆菌具有中等的抑菌效果,对大肠杆菌具有强抑菌效果,而对青霉菌的抑菌效果最好。Gd配合物、Tb配合物和Yb配合物的抑菌效果明显好于La配合物和Nd配合物,这说明中、重稀土配合物的抑菌性能好于轻稀土配合物。在室温条件下,5种稀土三元配合物对3种细菌的抑制作用,均可达一周时间以上,说明所合成的稀土三元配合物抑菌效果稳定。更多还原

【Abstract】 In this dissertation, we have prepared the complex of rare earth Schiff base 8-hxyquinoline via liquid-phase deposition, and studied their antimicrobial performance in detail. The ligand of Schiff base salicylaldehyde 5-aminosalicylic acid was obtained by the synthesis of salicylaldehyde and 5-aminosalicylic acid as the raw material. A class of new ternary rare earth complexes, prepared with in ethanol solution with rare earth (light rare earth La, Nd, middle rare earth Gd, Tb, heavy rare earth Yb) chloride, Schiff base salicylaldehyde 5-aminosalicylic acid and 8-hxyquinoline as ligand. The chemical composition, properties and bonding characteristics of the complex were identified by magnetic resonance spectra, infra-red spectra, UV-visible absorption spectra and DTA-TGA modern analytical techniques. Schiff base salicylaldehyde 5-aminosalicylic acid and 8-hxyquinoline participate in a four-tooth and two-tooth of coordination with the rare earth ion, and the coordinate number are 7 (for La and Nd)and 9 (for Gd、Tb and Yb), respectively. Through the studying of the antimicrobial effects test of the obtained ternary rare earth complexes, the results show that the complexes have different antimicrobial effects on the E.coli, bacillus subtilis and Penicillium, the complexes have a moderate antibacterial activity against bacillus subtilis, better antibacterial effect against E.coli, and best antibacterial effect against Penicillium. The antibacterial effect on the complex of Gd, Tb and Yb are better than the complex of La and Nd, which can be illustrated that the antibacterial of the complex of hight and middle rare earth are better than the complex of light rare earth. In addition, at room temperature, the antimicrobial effects of five kinds of rare earth ternary complexs to the three kinds of bacteria inhibition can keep more than a week, which can be indicated that the synthesized ternary complex have good stability antimicrobial effects.更多还原