【作者】 孙小钧；

【导师】 赵莺；

【作者基本信息】 成都中医药大学 ， 中医诊断学， 2009， 硕士

【摘要】 目的：通过对92例原发性痛风患者血尿素、血肌酐、血尿酸等临床资料的收集和研究,探讨这些检测指标与痛风四证型(风湿热痹、风寒湿痹、痰瘀痹阻、肝肾亏虚)之间的相关性,阐述其相关性的形成机制并筛选出一些特异性指标,以期辅助临床诊断治疗。方法：收集符合美国风湿病协会1977年制定的痛风诊断标准的原发性痛风患者临床相关资料并按中医辨证标准分型,对痛风中医证型分布规律及其与血尿素、血肌酐、血尿酸相关性进行分析。结果：1.本研究92例原发性痛风患者中以肝肾亏虚证多见。2.其肝肾亏虚组血尿素、血肌酐水平明显高于风寒湿痹组,痰瘀痹阻组,肝肾亏虚组,差异有统计学意义(P<0.01)。3.原发性痛风风湿热痹组与其他三组比较,血尿酸水平明显升高(P<0.01)。结论：1.原发性痛风中医证型分布及变化有其特定规律。2.可考虑将血尿素、血肌酐作为原发性痛风肝肾亏虚证辨证的临床参考指标。3.可考虑将血尿酸作为原发性痛风风湿热痹证临床辨证参考指标。更多还原

【Abstract】 Objective:This experiment was done to invest and study 92 cases of primary gout patient’s blood urea, serum creatinine, uric acid, explore the correlation between the four gout Syndromes (rheumatic fever Bi, Bi cold wind, phlegm and blood stasis block, liver and kidney deficiency) and these relevant indicators, as well as explain the formation mechanism of the relationship and select some specific indicators to support the clinical diagnosis and treatment.Methods:collect cases of gouty patients in according to the diagnostic criteria established by the Association of American College of Rheumatology in 1977. Divided these cases into 4 groups with the criteria of diagnosis of TCM Syndrome. Analyze the correlation between TCM Syndrome and Uric acid and other indicators.Results:1.The patten of liver and kidney deficiency was particarly prevanlent in 92patients whit primary gout.2. The patient’s serum creatinine and urea of liver and kidney deficiency groups was significance higher than the other three groups (P <0.01).3. The blood uric acid of rheumatic fever bi patients was significantly higher than the other three groups, the difference was statistically significant (P<0.01).Conclusion:1.The dispoinsition and changes of TCM patterns in patient with primary gout are peculiar.2. Serum creatinine and urea may be usd as the reference indexes for deficiency of liver and kidney during primary gout differentiation.3. Serum uric acid may be used as a differentiation indicator for rheumatic fever bi of primary gout clinical differentiation.更多还原