【作者】 郑莉；

【导师】 杨育霞；

【作者基本信息】 郑州大学 ， 电工理论与新技术， 2009， 硕士

【摘要】 随着科学技术的飞速发展,电磁辐射成为危害人们健康的重要隐患。经过国内外学者长时间的研究,发现电磁场对心血管系统会产生影响。所以,就有必要去研究电磁场对心血管系统的影响。本文在对心血管系统的生理知识和心血管系统建模的基本方法论证的基础上,采用建立电路模型与仿真的方法来研究电磁场对心血管系统的影响。分析了心脏、动脉系统的电路模型以及神经调节机制中的颈动脉窦-主动脉弓减压反射的数学模型。从能量角度和血流动力学角度详细阐述了生理上的耦合机制,并根据血液流动的基本参量与电学参量之间的比拟关系对心脏电路模型和动脉系统电路模型进行耦合,进行了MATLAB仿真。针对电磁场对心血管系统的影响主要是神经调节功能,进一步对模型加入神经调节机制的数学模型,进行正常生理情况下的仿真和分析,结果完全符合生理学上的心脏泵血机制,说明本文所建立的心血管系统的电路模型是正确的,与人体正常生理情况相符合。通过分析心血管系统的电磁生物效应的机理以及流行病学调查和动物实验,发现电磁波会引起交感传出频率和迷走传出频率发生变化,据此对模型相应参数进行调整,从外周血管阻力、心肌收缩能力和心动周期三个方面分别对电路模型进行仿真,用数字定量地说明了电磁场对心血管系统确实有影响,而且还会诱发疾病。更多还原

【Abstract】 With the rapid development of science and technology, electromagnetic radiation has become an important hidden danger to people’s health. After a long period of research, scholars at home and abroad have found that electromagnetic fields do have an impact on the cardiovascular system, and therefore, the impact is necessary to be studied.Based on the arguments of the physiological knowledge and the basic method of modeling of the cardiovascular system, this paper employs the methods of establishing the circuit model and simulating to study the impacts of electromagnetic fields on the cardiovascular system. It analyses the circuit model of the heart and arterial system and the mathematical model of the depressurized reflection of carotid sinus - aortic arch mechanism in the neural adjustment. From the perspectives of energy and hemodynamics, it details the coupling mechanisms in physiology, afterward, according to the compared relationship between the basic parameters of blood flowing and the electrical parameters, the circuit models of the heart and arterial system are coupled, besides, it is simulated with MATLAB. On the ground that the major impact of electromagnetic fields on the cardiovascular system is the neural regulation, it adds the mathematical model of the mechanism of neural regulation, simulates and analyses under normal physiological simulation. And the results fully consistent with the physiology of the heart pump mechanism, which illustrates that the cardiovascular system established in this paper is feasible and the circuit model accords with the normal physiological situation of the human body. Through the analysis of the mechanism of electromagnetic biological impacts on the cardiovascular system, the epidemiological investigations, and the animal experiments, it is found that the electromagnetic field will cause the changes of the sympathetic efferent impulse and vagal efferent impulse. Whereafter, the parameters of the model are adjusted accordingly, and the circuit model is simulated from the three aspects of the peripheral vascular resistance, myocardial contractility and cardiac cycle. It is described quantitatively with data that the electromagnetic field do affect the cardiovascular system and will induce diseases.更多还原