【作者】 郭维军；

【导师】 朱莹；

【作者基本信息】 湖南中医药大学 ， 中医内科学， 2007， 硕士

【摘要】 目的:1.观察益气消溃汤治疗脾虚挟热型Hp相关性消化性溃疡的临床疗效。2.探讨益气消溃汤治疗消化性溃疡,抗Hp感染的作用。方法:选择脾虚挟热型Hp相关性消化性溃疡60例,随机分为中药组、西药组、中西结合组,中药组给予益气消溃汤,西药组给予雷尼替丁、阿莫西林、甲硝唑西药三联疗法,中西结合组给予中西结合治疗,疗程为2周,停药1月后观察比较治疗前后各观察指标的变化。结果:1.胃镜疗效及中医证候疗效比较,中西结合组优于单纯中药组和西药组,差异有统计学意义(P＜0.05),中药组与西药组比较,差异无统计学意义(P＞0.05);2.中西结合组在改善临床症状方面更具优势,可明显改善胃脘疼痛、神疲懒言、肢体倦怠、食后腹胀、口干口苦、吞酸等临床症候。与西药组比较,差异有统计学意义(P＜0.05),但与中药组比较,差异无统计学意义(P＞0.05);3.三组Hp根除率比较,中西结合组稍优于中药组和西药组,但三组比较,差异无统计学意义(P＞0.05)。4.临床应用益气消溃汤过程中,未发现不良反应。结论:益气消溃汤结合雷尼替丁三联疗法治疗脾虚挟热型Hp相关性消化性溃疡疗效确切,可明显改善临床证候。益气消溃汤临床应用中未发现副作用,有其临床实用价值。更多还原

【Abstract】 Objctive:To observe the clinical effect of YiQiXiaoKui Decpction(YQXKD) in treating Hilicobacter Pylori-related Peptic Ulcer of Splenic Asthenia and Heat-inclusion(HPPUSAH) and counteracting Hilicobacter Pylori(Hp).Method:60 patients with YQXKD HPPUSAH were divided randomly into three groups:traditional Chinese drug treated group(20 cases),western medicine control group(20 cases) and the medium doctor combines cured group(20 cases).Traditional Chinese drug group was treated with YQXKD, while trilogy treatment of Ranitidine,Amoxicillin and Metronidazole was given western medicine control group,and two method was given The medium doctor combines cured group.The course of treatment is one month. The changes of patents’ clinical syndromes and indices were observed and compared before and after treatment.Result:Compared effect of gastro-scope and syndrome of traditional Chinese medicine,the medium doctor combines cured group is best.There were statistics differences between the two groups of the medium doctor combines cured and traditional Chinese drug treated(P＜0.05).But there were no statistics differences between the two groups of traditional Chinese drug treated group and western medicine cured group(P＞0.05).The medium doctor combines group was best in improving the clinical syndromes.It can effective against the patents’ clinical syndromes,such as stomach pain,mind tiredness,limbs languor,abdominal distention after meal,dry mouth,bitter taste of mouth,swallow sour etc.Compared with western medicine control group,there were significantly superior to those in western medicine group (P＜0.05).But there were no statistics differences between the two groups of traditional Chinese drug treated group and western medicine cured group (P＞0.05).The medium doctor combines cured group is best in deracinating Hp rate,but there were no statistics differences between any two groups (P＞0.05).There were no adverse in YQXKD clinical application.Conclusions:The effect of the medium doctor combines is certain in treating YQXKD HPPUSAH.It can effective against the patents’ clinical syndromes. It is effective and no side effect in YQXKD clinical application.更多还原