【作者】 鲁会杰；

【导师】 刘松江；

【作者基本信息】 黑龙江中医药大学 ， 中医学， 2009， 硕士

【摘要】 目的:观察用健脾益肾补气养血法指导的健脾益肾生血汤治疗晚期NSCLC患者血虚型癌性贫血的临床疗效。方法:按随机对照的方法把符合课题研究的晚期NSCLC合并血虚型癌性贫血的患者分组,共收集试验组30例、对照组30例。两组依据病情做相同标准的辅助治疗。对照组用铁剂、叶酸、维生素B₁2来改善贫血;试验组用铁剂、叶酸、维生素B₁2的同时加用健脾益肾生血汤来改善贫血。治疗2个月,观察贫血指标血红蛋白值（Hb）的变化、中医血虚证侯的改善情况,人体功能状态KPS评分的变化。结果:在Hb值方面,试验组改善56.67%,对照组改善23.33%,依据Ridit分析有统计学意义（p＜0.05）,说明试验组在改善Hb值方面优于对照组。在中医血虚证侯积分方面,试验组改善63.33%,对照组改善20%,依据Ridit分析有统计学意义（p＜0.05）,说明试验组在改善中医血虚证侯方面优于对照组。在KPS评分方面,试验组改善56.67%,对照组26.67%,依据Ridit分析有统计学意义（p＜0.05）,说明治疗后试验组人体功能状态改善优于对照组。结论:用健脾益肾补气养血法指导下的健脾益肾生血汤应用于晚期NSCLC患者血虚型癌性贫血,在提高Hb水平、改善中医血虚证侯、改善人体功能状态上,有明显的疗效。说明健脾益肾补气养血法在治疗血虚型癌性贫血方面具有显著疗效。更多还原

【Abstract】 Objective: To observe the clinical efficacy of Jianpi Yishen Buqi Yangxue Tang,which is under the guidance of Jianpi Yishen Buqi Yangxue Method,in treating Xuexu tumor anemia patients with advanced-stage NSCLC.Methods:Divided the Xuexu tumor anemia patients with advanced-stage NSCLC which met the demand.30 cases of test group and 30 cases of control group were collected.Both groups were treated with adjuvant therapy by the same standard.the control group used Iron, folic acid and vitamin B12 to improve anemia;the test group added Jian Pi Yi Shen Sheng Xue Tang.The time of treatment was 2 months.We observed the change situation of anemia indicator Hb and Chinese medicine symptoms of Xuexu,and the change of the body function KPS.Results: In the change of Hb values, the test group had 56.67% improvement and the control group had 23.33% improvement There was a significant on Ridit Analysis (p<0.05),It is said that the test group is better than the control group by improving the Hb value; In the change of the scores of Xuexu symptoms,the test group had 63.33% improvement and the control group had 20% improvement. There was a significant on Ridit Analysis (p<0.05),It is said that the test group is better than the control group by improving the Xuexu symptoms;To observe the change situation of KPS,the test group was 56.67% improvement,and the control group was 26.67% improvement,There was a significant on Ridit Analysis (p<0.05),It was said that the test group’s human functional state is better than the control group’s after treatment.Conclusion: The application of Jianpi Yishen Buqi Yangxue Method (Jianpi Yishen Shengxue tang) to tumor Xuexu anemia in patients with advanced NSCLC was effective.It can increase the Hb level and improve the symptoms of Xuexu .It also can improve the functional status of the human body.Jianpi Yishen Buqi Yangxue Method have good effect in treating Xuexu tumor anemia .更多还原