节点文献
益气养阴清热化痰法治疗肺癌发热的临床观察
Clinical Observation on the Treatment to Fever of Lung Cancer with Replenishing Qi to Nourish Yin and Clearing Heat and Resolving Phlegm Method
【作者】 郝晶；
【导师】 刘松江；
【作者基本信息】 黑龙江中医药大学 ， 中西医结合肿瘤， 2009， 硕士
【摘要】 目的:应用益气养阴、清热化痰法治疗肺癌发热,观察用药前后体温变化,中医临床症状及KPS评分变化,客观评价益气养阴、清热化痰法治疗肺癌发热的近期疗效,为中医治疗肺癌发热的治则研究提供临床支持,为研制新的治疗恶性肿瘤伴发热症中药制剂奠定临床基础。方法:选取40例肺癌发热(气阴两虚兼痰热证)患者,给予益气养阴、清热化痰法,进行口服中药治疗,并观察体温、中医临床症状及KPS评分的变化。结果:治疗后总疗效转归分析,总有效率90%;治疗后患者体温高热组体温比治疗前明显下降(P＜0.05),具有显著性差异;中等度发热组体温比治疗前明显下降(P＜0.05),具有显著性差异;低热组体温比治疗前明显下降(P＜0.01),具有显著性差异;患者KPS评分治疗后比治疗前显著提高(P＜0.01),具有显著性差异;治疗后中医症状除形体消瘦外,其它中医症状均明显改善(P＜0.01),具有显著性差异。结论:益气养阴、清热化痰法能明显降低肺癌发热患者的体温,改善中医症状,提高患者的生存质量,为研制治疗恶性肿瘤伴发热症的中药制剂奠定临床基础。
【Abstract】 Objective:Applying methords of replenishing qi to nourish yin,clearing heat and resolving phlegm to cure the fever of lung cancer,to observe the body temperature changes before and after medication,clinical symptoms and the changes of KPS score,objective evaluate the short-term effect in the treatment of fever of lung cancer with methord of replenishing qi to nourish yin,clearing heat and resolving phlegm method,to supply the clinical support for Chinese medicine treatment in fever of lung cancer,to establish the foundation for the development of new anti-cancer in Traditional Chinese Medicine.Method:40 cases of lung fever(Deficiency of both qi and yin and phlegm-heat) patients were selected,treating with methords of replenishing qi to nourish yin,Clearing heat and resolving phlegm method in Traditional Chinese Medicine.And observe the changes in body temperature,clinical symptoms and KPS score.Result:Analysis of the total effect of vesting,the total effective rate is 90%; KPS score after treatment in patients is significantly improved;the clinical symptoms after the treatment is significantly improved.Conclusion:the treatment with method of replenishing qi to nourish yin,clearing heat and resolving phlegm method,which can significantly reduce the body temperature of the lung cancer patients with fever,can improve the TCM symptoms and improve quality of life of patients,laying the clinical foundation for the development of new anti-cancer fewer Formulations in Traditional Chinese Medicine.