【作者】 迪丽白尔·塔力甫江；

【导师】 徐新娟；

【作者基本信息】 新疆医科大学 ， 内科学， 2009， 硕士

【摘要】 目的:探讨高血压伴焦虑抑郁症与肾素-血管紧张素-醛固酮系统及皮质醇浓度之间的关系。方法:对本院高血压科随机选择的65名高血压患者进行问卷调查,问卷调查的内容包括焦虑自评量表(SAS)和抑郁自评量表(SDS),同时给予这些患者抽血行卧立位肾素-血管紧张素-醛固酮及皮质醇节律检查。对相关数据采用X2检验、秩和检验及相关性分析。结果:高血压合并焦虑症患者与高血压不合并焦虑患者之间性别、凌晨1∶00皮质醇浓度及立位肾素存在差异,有统计学意义(P<0.05),高血压合并抑郁症患者与高血压不合并抑郁症患者之间凌晨1∶00皮质醇浓度有差异,有统计学意义(P<0.05),相关性分析时,高血压合并焦虑症患者与性别、凌晨1∶00皮质醇浓度存在相关性,高血压合并抑郁症与凌晨1∶00皮质醇浓度浓度存在相关性,有统计学意义(P<0.05)。结论:高血压合并焦虑抑郁症与性别、肾素水平、皮质醇浓度有关,皮质醇浓度越高,高血压合并焦虑抑郁症可能性越大。更多还原

【Abstract】 Objective: To investigate the relationship between hypertension companion depression or anxiety and renin level and cortisol rhythm. Methods: From our hypertensive department randomly selected 65 hypertensive patients conducted a questionnaire survey, questionnaire included self-rating anxiety scale (SAS) and self-rating depression scale (SDS), at the same time give these patients orthostatic lying blood renin -- angiotensin - aldosterone and cortisol rhythm checks. relevant data using X2 test, rank sum test and correlation analysis. Results: Gender, 1:00 am cortisol concentration and Orthostatic renin have statistical signifiance between hypertension companion anxiety and do not companion anxiety, 1:00 am cortisol concentration have statistical signifiance between hypertension companion depression and do not companion depression. By uesing correlation analysis, hypertension companion anxiety is related with gender,and 1:00 am cortisol concentration; hypertension companion depression is related with 1:00 am cortisol concentration. Conclusion: hypertension companion depression or anxiety is related with gender renin level,cortisol concentration,the higher level of renin and cortisol concentration the greater the likelihood of hypretension companion anxiety and depression.更多还原