【作者】 潘存雪；

【导师】 刘文亚；

【作者基本信息】 新疆医科大学 ， 影像医学与核医学， 2009， 硕士

【摘要】 目的:分析冠状动脉64层螺旋CT血管造影(CTA)的影像学表现,评价维吾尔族冠状动脉的形态学特征,并比较维吾尔族与汉族冠状动脉形态学的差异。方法:回顾性分析88例维吾尔族样本及与其匹配的88例汉族样本的64层螺旋CT冠状动脉CTA成像资料,并将两者的结果进行统计学分析比较。结果: 1.所收集88例维吾尔族冠状动脉CTA样本中,以右优势最多(64.77%);左冠状动脉开口以中1/3、窦内最多(73.86%,70.45%);右冠状动脉开口以右1/3、窦内最多(57.95%,64.80%);前、后降支,左回旋支,右冠状动脉的终止点分别以后纵沟下1/3(42.05%)、后纵沟中1/3(51.16%)、心左缘(59.09%)、左室后面(63.64%)最多;心肌桥发生位置以前降支(41.94%)最多。2.维吾尔族与汉族样本在以下方面的差别具有统计学意义:左冠开口位置纵向划分(T= 8319,P = 0.0331)、右冠开口位置纵向划分(T= 6936,P = 0.0331)、钝缘支个数(T= 7143,P=0.0214)、锐缘支发生率(x2=5.8381,P = 0.0157)、冠状动脉畸形发生率(x2= 5.1948,P = 0.0227)、冠状动脉畸形发生侧别(T=100,P=0.0213)、冠状动脉各种畸形所占比例(T= 106.5,P=0.0039)、冠状动脉各种变异所占比例(T= 6886.5,P=0.0242)、左冠各种变异所占比例(T= 2692,P=0.0008)、右冠各种变异所占比例(T= 968.5,P= 0.0153)。结论:64层螺旋CT冠状动脉CTA检查为冠状动脉形态学研究提供了一种实用的方法,借助于该方法,我们研究发现,维吾尔族冠状动脉形态具有其独特性,与汉族冠状动脉形态学特征相比,存在多项差异,这些差异一方面可能使两民族在冠状动脉造影术检查时的表现有所不同,从而提醒临床医师在行冠脉造影术操作时注意名族冠脉特点,以更好地进行操作;另一方面,可能和两民族的冠心病发病率及特点不同有一定程度的关联。更多还原

【Abstract】 Objective: To analysis the morphological findings of Coronary Angiography on 64 slice multiple CT (MSCT) and study the difference of coronary artery’s morphological characteristics between Uyghur and Han population in Xing Jiang. Methods: A study was made for 88 Uyghur samples and matched Han samples retrospectively, all the coronary images dates obtained by MSCTA were evaluated by 2 doctors respectively. Then the statistical comparison were made for this two groups. Results: 1.In the 88 Uygur coronary artery CTA dates“, right-dominant”is most regularly(64.77%); most of the left coronary artery originate from the middle 1/3 of the left aortic sinus(73.86%,70.45%),and most of the right coronary artery originate from the right 1/3 of the right aortic sinus(57.95%,64.80%); the most common ends of the Left Anterior Descending Branch(LAD), Posterior Descending Artery(PDA) ,Left Circumflex Artery(LCX),and the RightCoronary Artery(RCA) are the under 1/3 of the posterior interventricular groove(42.05%) , the middle 1/3 of the posterior interventricular groove(51.16%), the left side of the heart (59.09%)and the back of the left cardiac ventricle(63.64%); The highest incidence of the place of myocardial bridge is the anterior interventricular branch (41.94%).2. The coronary artery’s morphological characteristics of Uyghur population and Han population are different in following : the originate of the Left Coronary Artery(LCA) in vertical (T= 8319,P = 0.0331),the originate of the Right Coronary Artery(RCA) in vertical (T= 6936,P = 0.0331),the number of Obtuse Marginal Branch(OM)(T= 7143,P=0.0214),the rate of the Sharp Marginal Branch’s appearance(x2=5.8381,P = 0.0157),the proportion of coronary artery’s malformations(x2= 5.1948,P = 0.0227),the side of occurrence of coronary artery’s malformations(T=100,P=0.0213),the proportion of each kind of coronary artery’s malformations(T= 106.5,P=0.0039),the proportion of each kind of coronary artery’s variability(T= 6886.5,P=0.0242), the proportion of each kind of LCA’s variability(T= 2692,P=0.0008)and the proportion of each kind of RCA’s variability(T= 968.5,P= 0.0153).Conclusion: MSCT Coronary angiography provides a practical method for the study of the Minority’s coronary artery morphological characteristics.By this method ,we find that the coronary artery of Uygur exist a individuality and is different from the characteristics of Han.On the one hand ,these difference may relate to different pattens in Coronary angiography and clinicist should notice this ;On the other hand , these may relate to differences between Uygur and Han in the incidence and severity of CoronaryHeart Disease(CHD).更多还原