【作者】 赖晓霏；

【导师】 骆文龙；

【作者基本信息】 重庆医科大学 ， 临床医学， 2008， 硕士

【摘要】 目的治疗阻塞性睡眠呼吸暂停低通气综合征(OSAS)的方式很多,悬雍垂腭咽成形术(UPPP)是常见的手术方式。本文的目的主要在观察UPPP手术治疗OSAHS患者的临床疗效,并探讨如何评判阻塞性睡眠呼吸暂停低通气综合征(OSAHS)病的手术指征及围手术期的并发症的发生和预防。方法对来我科就诊以“打鼾、夜间憋醒”为主诉的病人,根据OSAS诊断标准并符合手术指征的286例的周围阻塞性OSAS病患者进行UPPP手术,根据其术前及术后整夜多导睡眠图检查(PSG)结果做自身对照分析。结果选择经PSG监测属于周围阻塞性OSAHS病的286例患者,其中轻度鼾症9例,中度鼾症23例,重度鼾症54例,分为三组组。分析三组病人的近期效果、手术范围及并发症。286例OSAS病患者中,术后较术前PSG监测指标(呼吸暂停总时间AI呼吸紊乱指数AHI血氧饱和度SaO2)均有显著性差异,AHl均<15,血氧饱和度SaO2:均>97%,治愈率达93%。结论UPPP手术是治疗OSAHS病效果较好的手术方法。尤其对于周围阻塞性OSAS病患者效果尤为明显,但是手术有一定的危险和并发症,因此掌握好手术指征和和切除反问非常重要,总之,悬雍垂腭咽成形手术操作简单,值得推广。UPPP的远期效果有待于进一步观察。更多还原

【Abstract】 Objective There are surgical many ways to cure obstructive sleep apnea syndrome(OSAS),among them uvulopalatopharyngoplasty (UPPP) have been widely used in clinic.This article is arm to observe the therapeutic effect of uvulopalatopharyngoplasty (UPPP) to patients with obstructive sleep apnea-hypopnea syndrome(OSAHS),and to explore a simple method to assess the surgical indications of these patients.Methods 286 patients with OSAS disease were treated with UPPP ,the results of PSG monitoring of the patients were divided into 2 groups according to these results of pre and post operations.Results The apnea index (AI)、apnea-hypopnea index (AHI)、SaO2 of postoperation were significantly different from that of preoperation.Conclusions UPPP is effective for OSAHS .Cases of peripheral obstructive and mixed patients are the best.Other cases cure result of the central site patients are not good.There is certain danger and complication in surgery group,so furthermore UPPP operation is simple and worth to promote.更多还原