【作者】 夏志林；

【导师】 伍林；

【作者基本信息】 武汉科技大学 ， 安全技术及工程， 2008， 硕士

【摘要】 本研究合成了没食子酸甲酯(MG)锆(MG-Zr)、没食子酸丙酯(PG)锌(PG-Zn)和没食子酸丙酯锆(PG-Zr)配合物并表征了的其结构,同时对没食子酸丙酯锌配合物的抗菌性能进行了初步研究。在水溶液中利用没食子酸甲酯或没食子酸丙酯和过渡金属(Zn、Zr)合成了三种新型配合物;通过紫外-可见光谱(UV-Vis)、中红外光谱(IR)、远红外光谱(far IR)、核磁共振氢谱(1H-NMR)和差热-热重(TG-DTA)等分析手段对三种配合物进行了表征,结果表明:过渡金属(Zn、Zr)可与没食子酸甲酯或没食子酸丙酯的酚羟基配位。配合物的紫外-可见光谱均与配体的有明显不同,吸收范围更宽,最大吸收峰发生了红移;羟基基团和苯环的IR光谱在配位后发生了位移和红移;在远红外吸收光谱中,配合物苯环的吸收峰较未配位的发生了分裂,且在320-480 cm-1处出现了新的M-O吸收峰;以氘代二甲基亚砜(DMSO-d6)为溶剂测定的没食子酸丙酯锌配合物的与没食子酸丙酯1H-NMR谱比较表明没食子酸丙酯的酚羟基上的O与金属离子发生配位,同时水分子参与了配位。通过连续稀释法实验可初步确定没食子酸丙酯锌配合物具有一定的抗菌性;没食子酸丙酯锌配合物的抗菌性能随着浓度的增加而增强;但是没食子酸丙酯锌配合物对不同菌种的抗菌性存在着较大的差异,对革兰氏阳性菌的抗菌性能明显优于革兰氏阴性菌。更多还原

【Abstract】 In this paper, the methyl gallate-Zr(MG-Zr), propyl gallate-Zn(PG-Zn) and propyl gallate-Zr(PG-Zr)complexes were synthesized and characterized, for the more, the anti-bacteria effect of PG-Zn were approached.Three new complexes were synthesized in water solution using transition metals(Zr, Zn)and gallic acid esters, including methyl gallate and propyl gallate. Three complexes were characterized by UV-Vis、IR、far IR、1H-NMR and TG-DTA spectra. The result shows that methyl gallate or propyl gallate ligands with Zr, Zn atoms through the phenolic hydroxyl. The UV-Vis spectrum of complexes and ligands are different. The UV-Vis region of each complex is wider and makes red shift when compared with its ligand. The mid-infrared spectra of between each complex and its ligand shows that the phenolic hydroxyl broad band change and the stretching vibration peaks of benzene ring shift. In the far-infrared absorption spectra of complexes, some peaks at 320-480 cm-1 are assigned to the stretching frequency of M-O. The 1H-NMR spectra of propyl gallate and propyl gallate-Zn in DMSO-d6 suggest that the coordinate bond formation takes place through the phenolic hydroxyl groups and water.The anti-bacteria function of propyl gallate-Zn was approached via continuously dilution method. The results show that the higher concentrations of propyl gallate-Zn, the better anti-bacteria function of propyl gallate-Zn, and the anti-bacteria function to gram-positive bacteria is better to gram-negative bacteria.更多还原