【作者】 吴军；

【导师】 何巍；

【作者基本信息】 广西医科大学 ， 外科学， 2008， 硕士

【摘要】 目的比较浅低温心脏不停跳和中低温停跳技术在婴幼儿心内直视手术的应用。方法分析56例3岁以下行心脏手术患者,其中26例(组Ⅰ)在中低温体外循环心脏停跳下手术,30例(组Ⅱ)在浅低温体外循环心脏不停跳下进行手术。比较两组患者的体外循环(CPB)时间、手术时间、术后呼吸机辅助时间、术后低心排发生率、术后严重心律失常发生率、术后住院时间以及死亡率情况。结果不停跳组患者的体外循环时间和手术时间均较中低温停跳组短(P＜0.01),并且术后呼吸机辅助时间也较停跳组短(P＜0.05);不停跳组患者术后的低心排发生率和严重心律失常发生率均较停跳组低(P＜0.05),并且术后住院时间也较停跳组短(P＜0.05)。结论浅低温体外循环心脏不停跳技术在婴幼儿心肌保护、改善术后呼吸功能以及促进患者恢复方面均优于中低温体外循环心脏停跳技术。表明浅低温体外循环心脏不停跳可作为一项安全、有效的技术应用于婴幼儿先天性心脏畸形的矫治。更多还原

【Abstract】 Objective: To compare the effects of mild hypothermia beating-heart cardiopulmonary bypass (CPB) with those of moderate hypothermia arrested-heat CPB in pediatric intracardiac procedure.Methods: 56 patients whose age were under 3 years underwent open heart surgery. In group 1, 26 patients underwent arrested-heart operation, and in group 2 ,30 patients underwent beating-heart operations.Duration of CPB and surgery ,postoperative mechanical respiratory assistance duration and incidence of low cardiac output, ect ,were compared between the tow groups.Results: Duration of CPB and operative duration in group 2 were shorter than those in group 1 (P<0.01),and postoperative mechanical respiratory assistance duration was shorter in group 2. The incidence of low cardiac output syndrome and serious cardiac arrhythmia in group 2 was lower than those in group 1, and postoperative residential duration was shorter in group 2.Conclusion: The effect of mild hypothermia beating-heart CPB is superior to that of moderate hypothermia arrested-heart CPB in pediatric cardiac surgery. Therefore, the mild hypothermia beating-heart CPB is a safe abd effective technique applied to pediatric cardiac surgery.更多还原