【作者】 陈凯龙；

【导师】 方坚；

【作者基本信息】 广州中医药大学 ， 中医骨伤科学， 2008， 硕士

【摘要】 研究目的本文通过临床研究主要观察中西医结合治疗对强直性脊柱炎(anylosingspondy-litls,AS)不同证型的临床疗效,以分析中西医结合治疗对何种证型强直性脊柱炎疗效最佳,从而为中西医结合治疗强直性脊柱炎提供一种可靠的疗效分析依据。研究方法本研究筛选强直性脊柱炎患者75例,按中医辨证分为湿热痹阻证、寒湿痹阻证、瘀血痹阻证、肾阳亏虚证、肝肾不足证五个证型,各组入组病例15例,分别观察治疗前后五个证型患者的主要症状、体征、实验室指标的变化。研究结果中西医结合治疗一个疗程(12周)后五个证型患者主要症状积分、体征积分、主要实验室指标自身前后对照或组间比较有显著或非常显著性差异(P＜0.05或P＜0.01)。湿热痹阻证总有效率为93.33%,寒湿痹阻证总有效率为93.33%,瘀血痹阻证总有效率为73.33%,肾阳亏虚证总有效率为86.67%,肝肾不足证总有效率为80%。结论中西医结合治疗对湿热痹阻证和寒湿痹阻证疗效接近且明显优于瘀血痹阻证、肾阳亏虚证及肝肾不足证;后三者中肾阳亏虚型优于肝肾不足型及瘀血痹阻证,瘀血痹阻型疗效与其他各组相比较最差。更多还原

【Abstract】 Objective:The artilcle was to evaluate the clinical curative effect of the combination treatment of traditional Chinese and western medicine on Ankylosing Spondylitis of Diffrerent syndrome tapes and discuss that which kind of type that the combination treatment of traditional Chinese and western medicine has the best effect on.Method:75 cases selecte vere selected,and were derided into five syndrome tapes according to syndrome differentiation base on traditional Chinese medicine.Compairing scores of symptom,physical sign and laboratory index after treatment with them before treatment.Results:After 12 weeks,there was significant or very significant difference of the scores of symptom,physical sign and laboratory index between the five type,compared with themselves or either of the five types.The total effective rate of damp and heat blocking syndrome was 93.33%,of cold and damp blocking syndrome was 93.33%,of deficiency of kidney Yang syndrome was 86.33%,of blood damp blocking was 76.33%,,of deficiency of liver and kidney syndrome was 80%.Conclusion:The effect of the combination treatment of traditional Chinese and western medicine on heat and damp blocking syndrome is similar to that on deficiency of cold and damp blocking syndrome,while is batter than the three tapes of the rest.The curative effect of deficiency of kidney Yang syndrome is batter than deficiency of liver and kidney syndrome,while the curative effect of blood damp blocking is the worst of five tapes.更多还原