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哈萨克族冠心病危险因素与冠状动脉病变程度的关系

Relationship between the Risk Factors of Coronary Artery Disease and the Severity of Coronary Artery Lesions in KAZAK Races

【作者】 达娜

【导师】 木胡亚提;

【作者基本信息】 新疆医科大学 , 内科学, 2008, 硕士

【摘要】 目的探讨哈萨克族患冠心病的危险因素与冠脉病变程度的关系。方法选择2002年1月-2007年5月在我院住院疑诊冠心病并行选择性冠状动脉造影检查的哈萨克族病人,对其发生冠心病的危险因素进行回顾性研究。结果选择性冠状动脉造影记录结果显示:两组间的血浆甘油三脂、糖化血红蛋白水平、高密度脂蛋白水平有显著性差异(P〈0.05)。病变组甘油三脂、糖化血红蛋白水平、年龄明显高于无病变组(P〈0.05)。两组血浆胆固醇水平无显著性差异。经回归分析表明,在哈萨克族中冠心病的病变程度与年龄(B=0.809,p= 0.005),甘油三脂具有显著回归关系(B=12.603,p= 0.000).与高密度脂蛋白水平无独立相关性(B=-4.502,p= 0.523)。与性别、高血压病程,胆固醇水平、糖尿病病程等因素无关。结论哈萨克族冠心病与高甘油三脂血症具有独立相关性。

【Abstract】 Objective To investigate the relationship between the risk factors of coronary artery disease and the severity of the coronary artery lesions in Kazak races. Methods A total of 123 consecutively admitted Kazak races patients were studied retrospectively. All patients suspected to have coronary artery disease and underwent a selective coronary angiography and a survey of risk factors during the hospitalization. Results Through Logistic regression analysis, advanced age, HTG ,were confirmed to be independent risk factors for coronary artery disease in KAZAK races.. And course of diabetes mellitus, course of hypertension, smoking, HTC were not confirmed to have great relationship with coronary artery disease in KAZAK races from the mult iple regression analysis. Conclusions different from the Han Nationality Relationship between the risk factors of coronary artery disease and the severity of coronary artery lesions in KAZAK races were confirmed as age,HTG, increase of HbA1c in blood plasma .

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