理肺疏肝汤治疗慢性阻塞性肺疾病急性加重期肺胀（肺虚肝郁痰浊内蕴证）机理探讨及临床研究

【作者】 邰长利；

【导师】 宫晓燕；

【作者基本信息】 长春中医药大学 ， 中医内科学， 2007， 硕士

【摘要】 目的：观察理肺疏肝汤治疗慢性阻塞性肺疾病急性加重期、肿胀(肺虚肝郁痰浊内蕴证)的疗效。方法：将60例肺虚肝郁痰浊内蕴证肺胀患者随机分为治疗组与对照组各30例。治疗组以调肝理肺宣畅气机祛痰化浊为治疗方法，予理肺疏肝汤(基本药物组成：柴胡、杏仁、葶苈子、厚朴、瓜蒌、浙贝、郁金、当归、白芍、桔梗)口服；对照组予蛇胆陈皮液口服。(武汉健民大鹏药业有限公司)结果：治疗组在主要症状、体征、舌质、舌苔、脉象及肺功能、血气分析方面与治疗前相比，均有显著或极显著差异(P＜0.05，P＜0.01)。组间比较，可见治疗组对上述诸方面的改善与对照组相比，均有显著性差异(P＜0.05)。总疗效分析，治疗组总有效率为86.67％，对照组总有效率为76.67％，治疗组显著优于对照组(P＜0.05)。结论：理肺疏肝汤能明显改善慢性阻塞性肺疾病急性加重期、肺胀(肺虚肝郁痰浊内蕴证)患者的临床症状，在一定程度上提高肺功能，疗效确切，无毒副作用。更多还原

【Abstract】 OBJECTIVE: To investigate the regulation liver and lung treating chronic obstructive pulmonary disease, acute exacerbation period, that lung inflation (phlem sultry Asthenic Lung and Liver depression syndrome) patient.METHODS: Liver depression and phlegm , sultry collection of 60 cases of lung deficiency type of lung inflation were randomly divided into treatment and control groups of the 30 cases. Transfer to the liver and lung treatment group, expectorant for treatment, transfer to the liver and lung soup (basic drugs: Bupleurum, Almond, Tinglizi, Houpo, Gualou, Zhebei, Yujin, Angelica,Baishao, Ballad) Oral;Control group were given Aminophylline tablets and Shedan Chenpi Oral Solution.RESULTS: In the treatment group,the main symptoms, signs,tongue,Tongue, pulse and lung function, blood gas analysis before and after treatment. There were significant or very significant difference (p<0.05,p<0.01). Group from the above comparison shows that the improvement in the treatment group compared with control group.There were significant differences (p<0.05) the total effect analysis, the treatment group, the total efficiency of 86.67%.The total efficiency of 76.67% for the control group, the treatment group was significantly better than the control group (p<0.05).CONCLUSION: Lifeishugan soup can inprove chronic obstructive pulmonary disease, acute exacerbation of clinical symptoms degrees period. Improve lung function can be better, more effective,non-toxic side effects.更多还原