【作者】 黄万福；

【导师】 张鹏飞；

【作者基本信息】 天津大学 ， 化学工程， 2006， 硕士

【摘要】 对异丙基苯胺是一种重要的有机合成中间体,其最主要用途是用作合成高效化学除草剂异丙隆的中间体,还可用于合成医药、染料、涂料及其它化工产品,因此开发对异丙基苯胺新的合成工艺前景广阔。传统对异丙基苯胺的合成方法环境污染和设备腐蚀严重。采用分子筛为催化剂合成对异丙基苯胺,可以避免环境污染和设备腐蚀,并适合于连续化生产,具有很好的实用价值。本文采用改进HWC-6型分子筛为催化剂进行苯胺-丙烯气液固三相烷基化反应。将苯胺-丙烯分子筛催化烷基化分别与苯-丙烯和苯酚-丙烯分子筛催化烷基化合成异丙苯和异丙基苯酚进行了对比,用估算方法得到苯胺与丙烯烷基化的反应热和反应物系临界参数等基础数据,采用Aspen软件确定了不同原料配比下反应物系的相图,由此确定烷基化反应的实验条件,在此基础上设计出等温积分式烷基化反应器。研究了不同反应条件对改进HWC-6型分子筛催化性能的影响,并对各因素的影响作了理论探讨,确定了最佳的反应条件。苯胺单程转化率达到66%,对位选择性75%。该工艺技术很好的解决了设备腐蚀、“三废”污染、生产成本高及无法实现大规模连续化生产等问题,为合成对异丙基苯胺开辟了一条新途径。更多还原

【Abstract】 p-Isopropylaniline is an important intermediate in organic synthesis. One of its main uses is to prepare high efficiency herbicide isoproturon. It can also be used in synthesizing medicine, dyestuff, coating and other chemical products. So there is a broad perspective to develop the synthesis process of p-isopropylaniline.Traditional processes for preparing p-isopropylaniline often lead to serious environmental problems and equipment corrosion. Preparing p-isopropylaniline over molecular sieve catalyst can provide a new way to avoid environmental pollution and equipment corrosion and also can be operated for continuous production. This technology has great practical application value.Alkylation of aniline by propylene was studied. Reaction was carried under gaseous and liquid mixed phase on modified HWC-6 zeolite molecular sieve. After comparison between alkylation of benzene and phenol by propylene and alkylation of aniline by propylene, some related data such as reaction heat and critical parameters were obtained by estimation methods, and a VLE chart within experimental condition was drawn according to calculation by Aspen software. Based on former comparison and calculation, appropriate experiment conditions were given and a continuous fixed-bed tubular reactor was designed for alkylation.The effects of different reaction conditions on modified HWC-6 have been inspected. The theoretical discusses according to the effects of different factors has been made, the favorite reaction condition has been determined. The converstion of aninline is up to 66%, selectivity of p-isopropylaniline is 75%.This technology could solve many existed problems, such as: the pollution of the three wastes, high production cost, equipment corrosion, difficulty in realization of series mass production. So it can be concluded that this technology developed a new path for the synthesizing of p-isopropylaniline.更多还原