【作者】 黄鹏；

【导师】 马依彤；

【作者基本信息】 新疆医科大学 ， 心血管内科， 2006， 硕士

【摘要】 目的：应用多普勒超声评价冠状动脉搭桥术前及术后心功能的变化。方法：选取81例行冠状动脉搭桥术的冠心病患者，按照有无心肌梗死，分为心肌梗死组和无心肌梗死组，再将心肌梗死患者按照有无并发室壁痛，分为室壁瘤组和无室壁瘤组，无心肌梗死组按照所搭血管桥，分为≤2支血管桥组和＞2支血管桥组，分别于术前、术后3个月应用经胸多普勒超声技术测量患者的左室射血分数(LVEF)、左室缩末容积(ESV)、左室舒末容积(EDV)、左心室每搏搏出量(SV)、左室短轴缩短率(LVFS)、二尖瓣舒张早期和舒张晚期峰值速度比值(E／A)。结果：术后无心肌梗死组和无室壁瘤心肌梗死组较术前LVEF、SV、EDV、E／A增大，ESV减小，所有指标间差异均有统计学意义；术后心肌梗死组和室壁瘤亚组各指标，及无并发室壁瘤亚组LVFS，比较术前差异无统计学意义：无心肌梗死组≤2支和＞2支血管桥亚组两组间，各相同指标手术前后的变化，无统计学意义。结论：冠状动脉搭桥术后左心室功能得到明显改善，但室壁瘤形成可能为冠状动脉搭桥术后心功能改善的一个不利影响因素。更多还原

【Abstract】 Objective: To assess the changes of left ventricular function after Coronary artery bypass grafting (CABG) with Doppler echocardiography. Methods: eighty-one patients of coronary artery disease, who had accepted CABG, were enrolled and grouped as: non-infraction, infraction, then infraction were grouped as aneurysm, without aneurysm, non-infraction were grouped as ≤2 bridges, >2 bridges. Left ventricular ejection fraction (LVEF), End-diastolic volume (EDV), End-systolic volume (ESV), Stroke volume (SV), Left ventricular fractional shortening (LVFS), E/A ratio, were measured by Doppler echocardiography before and 3 months after CABG. Results: Except infraction, infraction with aneurysm and LVFS in infraction without aneurysm, in non-infraction, infraction without cardiac aneurysm, LVEF, LVFS, SV, EDV and E/A increased, ESV decreased after CABG.Changes in ≤2 and >2 bridges had no difference. Conclusions: The results of this study suggest that the left ventricular systolic and diastolic function were improved in CAD patients progressed after CABG.. But cardiac aneurysm may have negative effect to left ventricular function.更多还原