1.秦艽炮制研究 2.《中国药典》2005版13种中药材薄层色谱彩色图谱

【作者】 高娟；

【导师】 王亚洲； 孙文基；

【作者基本信息】 西北大学 ， 中药学， 2006， 硕士

【摘要】 1.本文以秦艽为材料,采用高效液相的分析方法,以龙胆苦苷的含量为指标,研究了(1)秦艽药材分别在20℃、40℃、60℃、80℃、100℃、120℃、140℃、160℃、180℃、200℃干燥时,不同的干燥温度对秦艽中龙胆苦苷的影响;(2)秦艽的不同炮制方法即清炒、酒炒、阴干、暴晒、清蒸、酒蒸、奶煮对秦艽中龙胆苦苷含量的影响。结果发现秦艽药材在干燥的过程中,从20℃～100℃,龙胆苦苷的含量逐渐升高,在100℃时达到最高。从100℃～200℃,龙胆苦苷的含量逐渐下降,在200℃时含量降至最低。因此秦艽药材的最佳干燥温度为100℃。另外,对于不同的炮制方法来说,酒炒品中龙胆苦苷的含量最高,其次是清炒和暴晒。奶煮后的药材中龙胆苦苷的含量最少,这说明了秦艽传统炮制方法以及秦艽古方用药的的合理性,为秦艽饮片的质量标准的制定进行了基础性研究。 2.《中国药典》正文分药材和成药两部分,对于每一种中药材都有鉴别项,为了使鉴别项中薄层色谱鉴别更加规范化,药典委员会对2005版《中国药典》一部决定制定配套的《中药材薄层色谱彩色谱图集》。这一项目我们承担了13种中药材即桂枝、肉桂、仙茅、甘草、淫羊藿、土贝母、芫花、蒺藜、牛蒡、杜仲叶、南五味子、萹蓄、独活的标准彩色图谱的制定任务。这13种中药材薄层彩色图谱的制定都是以《中国药典》中各药材鉴别项下的薄层鉴别条件为主要依据,并参考大量的文献资料,在尽量不变动药典条件的基础上,对这13种中药材的彩色图谱做了标准化的研究,制定出了这13种中药材的标准彩色图谱。在研究的过程中,力求做到图谱的实用性、美观性、艺术性,并达到图谱信息的最大化,为2005版《中国药典》的做出更好实施贡献更多还原

【Abstract】 1 To improve the industrialization of Gentiana macrophylla Pall. in shaanxi province, using the HPLC to detect the gentiopicroside content as an index, we studied separately: (1) Influence of drying conditions on gentiopicroside content in Gentiana macrophylla Pall. (2) Influence of different processing technology on gentiopicroside content in Gentiana macrophylla Pall. At different drying temperature, the content of gentiopicroside is variable. When the drying temperature is at 20℃、 40℃、 60℃、 80℃、 100℃,the content of gentiopicroside is according to high and the highest is at 100℃, on the other hand the content is lower from 120℃ to 200℃. Conclusioning the gentiopicroside content is the hightest at the drying temperature of 100℃. Different processings such as baking with alcohol, baking with nothing. drying in the sun shine and cool, cook with milk, braise with alcohol and nothing, have much influence on the content of gentiopicroside.When it is baked with alcohol, the content is the higtest. On the other hand it si lowest when it is cooked with milk. This can provid some reason to the processing technology method, which is useful to the quality standard of Gentiana macrophylla Pall.2 Pharmacopoeia of People’s Republic of china is a low of medicine and traditional herbal medicine. Every herb in it has its own distinguish of thin layer chromatography. In order to improve its legal fiction, the committee of Pharmacopoeia of People’s Republic of china established a collection of chromatic illustrative plates of planar chromatography TLC, which is matched with Pharmacopoeia of People’s Republic of china(2005). The meeting of Pharmacopoeia of People’s Republic of china(2005) granted the task of thirteen herbs to us in order better to describe the quality of Chinese traditional medicine, we studied the thirteen herbs separately and established their collection of chromatic illustrative plates of planar chromatography TLC. Referrencing other article, we main use the condition of Pharmacopoeia of People’s Republic of china(2005) to make the collection. The collection of chromatic illustrative plates of planar chromatography TLC is not only practicability, artworkly and beautiful, but also in the fully person of information of herbs.更多还原