【作者】 艾尼娃尔·艾克木；

【导师】 热娜·卡斯木；

【作者基本信息】 新疆医科大学 ， 生药学， 2005， 硕士

【摘要】 黑种草为毛茛科（Raunnculaceae）黑种草属（Nigella）植物,一般药用部位为种子,目前作为药用的3个种,分别为瘤果黑种草,又名腺毛黑种草;果黑种草,又名家黑种草（Nigella sativa L.）;以及黑种草。瘤果黑种草（Nigella glandulifera Preyn et Sint）为新疆维吾尔族习用药材,维吾尔族名为斯亚旦,瘤果黑种草在新疆大部分地区都有种植如:吐鲁番、善鄯等地。在新疆大部分药材市场都可买到,应用极广。 新疆黑种草子（Nigella glandulifera Preyn et Sint）的化学成分的研究国内外都比较少。因此有必要对化学成分进行近一步的研究。 本课题以新疆黑种草子为研究对象,从正丁醇萃取部分、80%醇提后乙酸乙酯萃取后剩余未萃取部分和石油醚萃取部分分离的到6个化合物,并用化学方法和光谱方法(¹H-NMR、¹³C-NMR、MS等)对其中5种化合物进行了结构鉴定,它们分别是:化合物（V5-20）黑种草甙(C₃₃H₄₀O₂₁);化合物（AI-2）β-谷甾醇(C₂₉H₅₀O);化合物（AI-4）蔗糖(C₁₂H₂₂O₁₁;化合物（AI-5）胆甾醇(C₂₇H₄₆O);化合物（AI-6）亚油酸(C₁₈H₃₀O₂);化合物（AI-3）豆甾醇(C₂₉H₄₈O)。而（AI-5）胆甾醇(C₂₇H₄₆O);（AI-6）亚油酸(C₁₈H₃₀O₂)是首次从此植物中分离得到。更多还原

【Abstract】 Nigella glandulifera Preyn et Sint belongs to Nigella of Raunnculaceae, and the seed of the plant is used as medicine. It distributes in tulufan shanshan of Xinjiang.Nigella glandulifera Preyn et Sint is the traditional herb of minority in Xinjiang. It has aboundant resource, considerable reserves. Many chemical constituents were obtained, which were Nigeglanoside, Nigeglanose, Cyclolandenol, β-sitosterol, Saccharose, Fuzitinechloride, and ect.Nigella glandulifera Preyn et Sint is special herb in Xinjiang, have been considered as one of the valuable herb to develop. We studied the chemical constituents of Nigella glandulifera Preyn et Sint, and isolated six compounds from n-Butanol extract fraction and Petroleum ether extract fraction, and they were testified by chemical and spectrum means such as UV, 1^H-NMR, （13）^C-NMR and etc. They are β-sitosterol (C₂₉H₅₀O), Saccharose (C₁₂H₂₂O₁₁), cis-Octadecy1-9, 12-diene (C₁₈H₃₀O₂), cholesterol (C₂₇H₄₆O), stigmasterol (C₂₉H₄₈O) and Nigeglanoside (C₃₃H₄₀O₂₁) .Cholesterol and cis-Octadecyl-9, 12-diene were isolated from Nigella glandulifera Preyn et Sint in Xinjiang for the first time.更多还原