【作者】 吴楚君；

【导师】 韩景光；

【作者基本信息】 湖南中医学院 ， 中西医结合神经外科， 2004， 硕士

【摘要】 目的：探讨中西医结合治疗重型原发性颅脑损伤急性期的临床疗效。 方法：62例重型原发性颅脑损伤急性期住院病人(格拉斯哥昏迷评分(GCS)＜8分，原发性昏迷时间＞12小时，外伤史＜3周)随机分为2组；治疗组(31例)，对照组(31例)。治疗组在西医治疗的基础上予以龙琥醒脑汤口服，对照组单用西医治疗。 结果：治疗组显效率(29.03％)，有效率(38.71％)及总有效率(83.87％)，明显高于对照组(分别为19.35％、16.13％、64.51％)，P均＜0.05，治疗组脑外器官系统受损率，机体代谢紊乱发生率及高热等并发症发生率明显少于对照组，GCS评分提高快于对照组，而昏迷持续时间明显少于对照组(P＜0.05)。 结论：中西医结合救治重型原发性颅脑损伤有显著疗效，中药在一定程度上阻止了重型原发性颅脑损伤急性期病理改变的恶性循环，缩短了昏迷时间，降低了致残率，提高了患者的生存质量。更多还原

【Abstract】 Objective: To explore the curative effect on integrated traditional Chinese medicine and western medicine (TCM - WM) therapy in treating acute stage of severe primary craniocerebral injury.Methods Sixty-two patients[G lasgow coma scole(GCS)<8 scors, coma time>12 hours ,injury time<3 weeks] were randomly divided into two groups:the treatment group(n=31) and the control group (n=31).Based on conventional WM therapy the former group was treated with Longhuxingnao decoction(#),and the latter was treated with WM alone.Results: Statistical analysis of results showed that the markedly effective rate(29.03%),effective rate(38.71%)and total effective rate(83.87%)in treatment group were significantly higher than those(19.35%,16.13% and64.51%,respectively)in control group(all p<0.05).The incidence rate of multiple organ damage, metabolism disorders, and fever etc. in treatment group were obviously lower than those in control group. The GCS scores were improved more rapidly in treatment group than those in control group. While the coma time in form group was significantlyshorter than that in latter group.Conclusion: The Longhuxingnao decoction may inhibited ricious cycle in the histopathological changes of severe primary craniocerebral injury to a certain extent.There are significant curative effects in severe primary craniocerebral injury treated with TCM-WM therapy can shoren the coma tima, reduced disability rate ,improve quality of life on severe primary craniocerebral injury.更多还原