【作者】 田园；

【导师】 顾向应；

【作者基本信息】 天津医科大学 ， 妇产科学， 2004， 硕士

【摘要】 目的：观察纳米银抗菌剂(商品名为阿希米，asimi)治疗各种阴道炎的效果。方法：采用随机对比性临床研究，对400名患有各种类型阴道炎的妇女进行临床观察，将纳米银的治疗效果与目前常用的各类治疗阴道炎的药物的疗效进行比较，比较项目包括：症状、体征、实验室检查、患者对于药物的感受等方面的情况。结果：纳米银对滴虫性阴道炎、念珠菌性阴道炎、细菌性阴道病、其它类型阴道炎的治疗有效率分别为75.47％，93.62％，79.17％，95.35％。纳米银对支原体感染的有效率为68.1％，转阴率为15.38％，对衣原体感染的有效率为88.2％，转阴率73.68％。纳米银治疗后支原体感染定量值降低情况优于常规组。纳米银对滴虫性阴道炎、念珠菌性阴道炎、细菌性阴道病的治疗效果与常规药相比没有显著性差异，对其它类型阴道炎的治疗效果优于常规药物。患者对于纳米银的治疗感受优于常规药物。结论：纳米银抗菌剂治疗阴道炎是一种安全、有效、广谱、不易产生耐药、易于为患者接受的治疗方法，其优势在于在无完善的实验室检查下仍可对患者进行治疗，并可作为支原体、衣原体感染预防和治疗的局部用药。更多还原

【Abstract】 OBJECTIVE: The aim of the present study was to observe the curative effect of asimi to vaginitis. METHODS: Random-controled clinical study. 400 women with various kinds of vaginitis were bring into the study. Compare the curative effect of asimi with medicine for vaginitis in common use. Observe their effect to symptom, physical examination and laboratory examination, after curative patients were asked to answer their recept to the medicine they were used. RESULTS: The efficient of asimi to trichomonas vaginalis, Candida vaginitis, bacterial vaginosis, other vaginitis were 75. 47%, 93.62%, 79.17%, 95. 35%. The efficient of asimi to chlamydia trachomatis was 68.1%, the turned negative ratio was 73.68%. The efficient of asimi to ureaplsma urealyticum was 88.2%, the turned negative ratio was 15.38%. The curative effect of asimi to chlamydia trachomatis and ureaplsma urealyticum was better than medicine for vaginitis in common use. The treatment results of the two groups of trichomonas vaginalis, Candida vaginitis, bacterial vaginosis had no evidence different, but to other vaginitis group asimi’s curative effect was better than medicine in commun use. CNCLUSION: Use asimi to deal with vaginitis was a safety, effective, easy to be accepteded therapy. The virtue of asimi was that it can used directly to those patients whom hadn’t had any laboratory examination, and could be used as the curative or defend medicine of ureaplsma urealyticum and chlamydia trachomatis infection .更多还原