【作者】 卢言平；

【导师】 毕荣修；

【作者基本信息】 山东中医药大学 ， 中医骨伤科学， 2004， 硕士

【摘要】 颈椎病是危害中老年人健康的常见病和多发病，神经根型发病率最高，在颈椎病各型中，占50-60%，本研究运用葛芪二仙汤治疗神经根型颈椎病，并从理论、临床、实验三个方面对其改善神经根颈椎病的症状的基理进行探讨。本研究表明气滞血瘀而致经脉痹阻不通是其重要病机，据此确立活血化瘀、通络止痛为主、兼顾补益肝肾、益气养血的治疗方法，组成葛芪二仙汤。临床对138例颈椎病患者进行了一个月系统的观察，发现葛芪二补汤能有效改善患者的症状，总有效率达到93． 59%，明显优于对照组颈复康(P<0． 05) 。根据颈椎病的病理机制，制造动物模型，从实验研究的角度证明了葛芪二仙汤的口服安全性、抗炎镇痛、改善血液粘度和微循环的作用。另外，从中、西医理论的角度对与本研究有关的问题进行了讨论。更多还原

【Abstract】 The Cervical Spondylosis(CS) which endangers the elderly’s health is a common and frequently-occurring diseases, The type of root of nerve has the highest incidence of disease which accounts for 50% - 60% of various CS. This study uses Ge Qi Er Xian Tang(GQEXT) to treat nerve- root -type CS, and at theory, clinical, experiment three respects to probe into the basic theory of improving the main symptoms of nerve- root -type CS . This research shows that nerve- root -type CS is closely connected with Qi Stagnation and blood stasis which lead to Bi-syndrome,so GQEXT is composed on the basis of therapy of invigorating blood circulation and dispersing blood stasis, invigorating pulse-beat and relieving pain,reinforcing liver and kidney and strengthening Qi and nourishing blood.In clinical study,the 138 cases of nerve- root -type CS were treated and observed systematically for a month.And the results show that GQEXT can effectively improve the symptoms of nerve- root -type CS.The totally effective rate amounts to 93.59% and significantly superior to the control group-Jing Fu Kang(P<0.05).In terms of the pathogenesis of nerve- root -type CS we designed the animal modles and engaged in the experiments.The experimental results show that GQEXT has vocal safety and many aspects including inflammatory and relief of pain ,improvement of the blood viscosity and microcirculation.In addition,the questions relevant to this study were discussed in the perspective of TCM and western medicine.更多还原