【作者】 吕艳锋；

【导师】 蒲斌；

【作者基本信息】 山东中医药大学 ， 中医外科学， 2004， 硕士

【摘要】 粘连性肠梗阻(Adhesive Intestinal Obstruction,AIO)是肠梗阻最常见的一种类型，发生率高，至今仍是临床上尚未解决的外科难题。本课题在中西医结合理论指导下，对腹部外科手术患者，开展了清肠饮合剂肛门滴注预防术后粘连性肠梗阻的临床观察与实验研究。本课题以尽早恢复胃肠动力、缩短肠管创面间固定接触时间为立足点，与大承气汤组及单纯西医治疗组进行对比观察，结果提示，在术后肠鸣音恢复时间、首次排气时间、排便时间、胃动素浓度等指标方面，清肠饮合剂组与大承气汤组及空白组相比均有显著性差异(p<0． 05) 。追踪回访发病情况，清肠饮合剂组没有发病，低于大承气汤组(10． O％)和单纯西医治疗组(25． 0％)。在实验研究中，清肠饮合剂组胃动素水平高于大承气汤组和单纯西医治疗组，经统计学处理有显著性差异(p<0． 05) 。表明，清肠饮合剂具有促进胃肠运动功能恢复的作用，用于防治术后粘连性肠梗阻有较好的效果。更多还原

【Abstract】 Adhesive Intestinal Obstruction(AIO) often occurs during the post-operative time,as a complex problem to surgeons.Under the theory of combining with the Chinese and western medicine,clinical and experimental study was carried out in the operational patients of abdomen that prevent post-operative AIO with QingChangYin HeJi by intraanus perfusion.The study aimed at comeback of intestine and stomach function,compared with group of Da ChengQi soup and simple western treatmentThe clinical study showed that QingChangYin HeJi group had obvious difference with Da ChengQi soup and blank groups(p<0.05), in comparison with the gurgling sound resume time,exhaust and defecate time,the level of Motilin (MLI) .The follow-up showed that the morbidity of QingChang Yin HeJi group was far lower than that of Da ChengQi soup(10.0%) and simple western treatment groups(25.0%).The experimental study indicated that the level of MLI in QingChang HeJi group was higher than that of the other two groups(p<0.05). QingChang Yin HeJi can help to quicken comeback of intestine and stomach function and prevent post-operative AIO.更多还原