【作者】 王金环；

【导师】 孙伟正；

【作者基本信息】 黑龙江中医药大学 ， 中医内科学， 2004， 硕士

【摘要】 为验证补髓生血颗粒治疗慢性再生障碍性贫血(chronic aplastic anemia，简称慢性再障，CAA)的疗效，比较补髓生血颗粒与再障生血片的疗效及外周血象、骨髓象和贫血程度的差异，本研究对62例CAA患者进行了观察研究。 结果表明，补髓生血颗粒能明显提高外周血血红蛋白、白细胞、血小板、网织红细胞和嗜中性粒细胞水平和降低淋巴细胞水平，提高骨髓增生度，降低非造血细胞百分比，减轻CAA患者的贫血程度，与疗前相比有显著差异或非常显著差异(P＜0.05，P＜0.01)。补髓生血颗粒治疗CAA的有效率为78.13％，优于再障生血片的有效率53.33％(P＜0.05)。 本研究还观察了CAA肾阳虚型和肾阴虚型患者治疗前后贫血程度、骨髓象和外周血象的变化情况以及疗效情况，结果发现治疗后除了血小板水平两型相比无显著差异(P＞0.05)外，其余指标两型相比均有显著差异(P均＜0.05)，从而在一定程度上验证了中医“阳虚易治，阴虚难调”这一理论的正确性。更多还原

【Abstract】 For testing the effects of Marrow-supplementing and Blood-engendering Granule (MSABSEG) working on CAA and the difference between Marrow-supplementing and Blood-engendering Granule (MSABSEG) and Aplastic Anemia Blood-engendering tablet (AABET), 62 CAA patients’ peripheral hemogram, myelogram and anemia degree before and after treatment were compared in this experience.It was found that MSABSEG could significantly or very significantly (P<0.05, P<0.01) increase the level of peripheral hemoglobin, leukocyte, platelet, reticulocyte and neutrophil, decrease the level of lymphocyte, stimulate the growth of bone marrow, depress the level of non-hematopoietic cells, reduce the anemia degree. The effective rate of treating CAA with MSABEG hit 78.13%, higher than that of AABET 53.33%.In the experience peripheral hemogram , myelogram and anemia degree before and after treatment beween Kidney-yang vacuity and kidney-yin vacuity were also compared.It was found that all the indes of Kidney-yang vacuity were better recovered than that of Kidney-yin vacuity (P<0.05). This proved the theory "Easy to cure Kidney-yang vacuity and Difficult to cure Kidney-yin vacuity".更多还原