非创伤性股骨头缺血性坏死的病因病机研究进展及109例股骨头缺血性坏死病因学调查分析

【作者】 徐王兵；

【导师】 邓友章；

【作者基本信息】 成都中医药大学 ， 中医骨伤科学， 2004， 硕士

【摘要】 非创伤性股骨头坏死是骨科临床上的常见病、疑难病。中医学无相同病名记载，但认为其病因病机多为摄身不慎，外感六淫，饮食内伤，导致肝肾亏虚，气血失调，筋脉失养所致。治疗上亦多从补肝肾、活血化瘀以及化痰祛湿着手。现代西医学对本病的病因及发病机理进行了积极的探索，在对其发病原因方面进行大量的流行病调查及实验研究。认为本病的发病原因有以下几个方面：1、激素 2、酒精 3、辐射 4、血液系统疾病 5、血管源性疾病 6、其他等。其发病机制与静脉内瘀滞，骨内压升高；脂质代谢紊乱；微血管损伤；骨质疏松等有关。本文将对中西医近二十年来对该病病因及发病机制的研究进展作一综述，提出本病研究过程中存在的一些问题及今后研究探讨中应注意的几个方面。并附成都中医药大学附属医院2001年11月～2003年11月年骨科门诊及住院109例非创伤性股骨头坏死病因学调查，结果认为：激素是导致该病的首要因素，酗酒位居第二位，但近年来由于酗酒导致本病的病例日趋增多。因此应加强对医务人员科普知识的学习和对吸烟、饮酒等高危人群的宣传教育，减少本病的发生。更多还原

【Abstract】 Nontraumatic osteonecrosis of the femoral head is a common disease in osteopathy clinic which is difficult to be treated.There is no record of "ANFH"in TCM,but its’ pathogenesis usually due to the irregularity in daily life affection by external six Evils,eating and drinking without temperance,which cause the Deficieny of both Liver and Kidney,Disfuction of the Liver and Kidney , disharmony between Qi and Blood. Its’ therapetic methods always use tonify Liver and Kidney , promont Blood circulation to dissipate Blood stasis and resolve Phlegm and diapel Dampness eta. Western medicine study on its pathogenic causes and mechanism.and have made lots of experiments and epidemiology . There are six facters in its pathogenic causes:1 steroid-induced 2 alcohol-induced 3 radiation 4. blood diseases 5 blood vessel related disease 6 other factors eta.Its mechanism is related with stasis in vein.bone marrow pressure rising;fat metabolic disorder;microvessel damage; osteoporosis eta. This paper provides a comprehensive report on the accomplishment of TCM and western medicine on pathogenisis and mechanism of ANFH in last 20 years.and provides problems during the research,and exploring in the future.Meanwhile we did a Epidemiology of the pathogenisis of 109 patients that come from the osteopathy clinic from December,2001 to December,2003 of the teaching hospital of chengdu university of TCM. The results:orticosteroid is the first factor,alcoholic is the second.But in recent years,there are more and more patients cause by alcoholic,and it always accompany with smoking.So we should stronger the study of popular science to to doctors and nurses.treat disese by hormonecarefully.and give publicity to the high risk people to preventing the ANFH.更多还原