超快速核磁共振成像（Ultrafast MR Imaging）在阻塞性睡眠呼吸暂停综合征阻塞部位判定中的临床意义

【作者】 陈彦如；

【导师】 孙炜；

【作者基本信息】 青岛大学 ， 耳鼻咽侯科学， 2001， 硕士

【摘要】 目的 通过超快速磁共振成像（Ultrafast magnetic resonance imaging，超快速MRI）对阻塞性睡眠呼吸暂停综合症（obstructive sleep apnea syndrome，OSAS）阻塞部位进行定位研究，并探讨将两种方法联合应用以提高改良UPPP手术疗效。 方法 对16例患者术前术后行PSG、MRI、FNMN及各径线测量，然后对其中的15例进行手术。分别对其术前术后结果进行分析。 结果（1）使用超快速MRI筛选改良PPP适应证病例，，阻塞部位位于SP，手术获得满意疗效；阻塞位于SP+LP+EP者，手术疗效较差。（2）16例行两种检查的患者，13例二者检查结果一致。另外其余3例患者，2例在FNMN检查示SP阻塞，而MR显示有SP+LP阻塞；1例FNMN示SP+LP+EP均有阻塞，而MRI示EP并未阻塞。经相关回归分析证实：两种检查结果具有相关性。（3）LP与EP阻塞在术后均有不同程度的减轻。 结论 应用超快速MRI对改良PPP手术患者进行筛选，可提高手术疗效，对确定诊疗措施有一定指导意义。更多还原

【Abstract】 Objective We attempted to determine the usefulness of Ultrafast MR Imaging examination in positioning the obstructive sites in patients with OSAS.Methods A total of 16 patients with OSAS underwent Ultrafast MR Imaging examination, while after i.v. injection of hydroxyzine hydrochloride. Serial imagines of 15 patients were examined before and after UPPP. Pharyngeal finding on MRI were divided into: (1)Soft Palate level,SP or Velopharynx level, (2) Lingual Root level，LR or Glosspharynx level,(3) Epiglottis level，EP. PSG findings were analyzed to determine the severity of obstructive sleep apnea as evaluated by AHI and the lowest SaO2 value during sleep. We also used fiberoptic nasopharyngoscopy with Muller’s maneuver，FNMN before and after surgical method and compared the findings with Ultrafast MR Imaging examination.Results (1)UPPP succeeded when MRI findings showed the obstructive sites in SP ,while in SP+LP or SP+LP+EP, UPPP was less useful. (2)Compared with findings in MRI imagines and FNMN, we found there <WP=5>were corresponds between them.Conclusion Analysis of pharyngeal dynamics using Ultrafast MR Imaging may provide some useful information for promoting the successful rate of UPPP.更多还原