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良导络调节疗法下穴位贴敷复方南星止痛膏治疗膝骨性关节炎的临床研究

The Clinical Research of Ryodoraku Regulation Therapy Using Fufangnanxingzhitong Plaster Acupoint Application on Kneel Osteoarthritis Patients

【作者】 陈海东

【导师】 王培民;

【作者基本信息】 南京中医药大学 , 中医学, 2012, 硕士

【摘要】 [背景]良导络疗法是通过选择适当的治疗点来调整全身良导络,使之恢复生理平衡状态的一种方法。对于膝骨关节炎而言临床多见关节疼痛、肿胀、肢体沉重、功能障碍等症状,与中医经络理论中“输穴”所主相似,因此选为良导络疗法的治疗点。穴位贴敷是中医的特色疗法之一,它在消化系统、呼吸系统疾病的治疗方面有着独特的优势,也已有学者将其应用于骨关节炎的治疗中。将良导络疗法与穴位贴敷相结合治疗膝骨关节炎是本研究的创新之处。复方南星止痛膏治疗骨性关节炎具有良好的疗效,已经广泛应用于临床,该药被选为本研究的贴敷药物。[目的]本课题从文献研究、临床研究两个方面着手,评价良导络调节疗法穴位贴敷复方南星止痛膏治疗膝骨关节炎的临床疗效,并且探讨其与中医经典理论的联系。[方法]本研究为前瞻性、随机、对照研究。总共60例(有效55例)年龄介于40-75岁的江苏省中医院门诊膝骨关节炎患者随机分成治疗组和对照组,治疗组予以良导络调节疗法穴位贴敷复方南星止痛膏治疗,对照组给予常规复方南星止痛膏贴敷治疗。连续用药2周,观察治疗前后的疼痛、僵硬、功能障碍VAS评分、WOMAC指标积分。全部病例治疗观察结束后进行统计分析。[结果]良导络测定膝骨关节炎患者的F1脾经、F4膀胱经兴奋,同时伴有F3肾经、F5胆经抑制现象最为明显。各组组内前后比较在疼痛、僵硬、功能障碍单项积分以及WOMAC总分、OA整体评分、总有效率方面都有显著差异(P<0.05),治疗后两组组间比较在疼痛、功能障碍单项积分以及WOMAC总分方面有显著差异(P<0.05)。提示良导络调节疗法穴位贴敷复方南星止痛膏组疗效优于常规复方南星止痛膏贴敷组。

【Abstract】 [background] Ryodoraku Regulation Therapy is one of the treatment Methods which can make the Ryodoraku in physiological balance by selecting the appropriate treatment points. To knee osteoarthritis, Joint pain, swelling, limb heavy and dysfunction are comm clinical symptoms which similar with Shu acupuncture point master.So it was selected as the Ryodoraku Regulation Therapy acupuncture point.Acupoint application is one of the features of TCM treatment. It has unique advantages in treatment of the digestive system and respiratory system diseases. And s scholars are also applied it in the treatment of osteoarthritis.Two combining treatment of osteoarthritis of the knee is the study of innovation. Fufangnanxingzhitong Plaster has good therapeutic effect to osteoarthritis and widly used in the clinical.So the application drugs is Fufangnanxingzhitong Plaster.[objective] This was a prospective randomized active control trial. To evaluate clinical efficacy of Ryodoraku Regulation Therapy using Fufangnanxingzhitong plaster acupoint application in the treatment of knee osteoarthritis and to assess its relation with classical theory of TCM.[Methods] This was a prospective randomized active control trial. A total of60(56effective) participants with OA of knee joints between38and75years old from the outpatient department of Jiangsu Provincial Hospital of TCM were randomly assigned to receive Ryodoraku regulation therapy using Fufangnanxingzhitong plaster acupoint application and regular treatment using Fufangnanxingzhitong plaster of the affected knee joints. All cases were followed clinically for a minimum of2weeks and the main observe VAS indexes of pain, stiffness, dysfunction of WOMAC scores were recorded. The data was statistical analyzed in the end.[Conclusion] An integrated approach of Ryodoraku regulation therapy using Fufangnanxing-zhitong plaster acupoint application is better than regular treatment using Fufangnanxingzhitong plaster as an effective treatment which fully embodies the characteristic of TCM in alleviating pain, improving knee disability and quality of life in patients with OA knees with less adverse reaction. It proves that this disease is attributive to deficiency complicated by excess while the endogenous factors are deficiency of the liver and kidneys, and cold-damp invasion of spleen.

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